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Rrm2 cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Rrm2 cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:12401
  • Region Covered
    full length cDNA
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    ~2.1 kb
  • Note
    Clone 10 and Rrm2 cDNA are similar probes. Rrm2 cDNA is also referred to as Clone 22 and will hybridize with Rrm2-ps1, Rrm2-ps2, and Rrm2-ps3. Subcloned into pUC18.
  • Synonyms
    Clone 22
Source
  • Species
    mouse, laboratory
  • Tissue
    mammary gland
  • Cell Line
    tumor cell line TA3
Genes
Rrm2 ribonucleotide reductase M2
Rrm2-ps1 ribonucleotide reductase M2 pseudogene 1
Rrm2-ps2 ribonucleotide reductase M2 pseudogene 2
Rrm2-ps3 ribonucleotide reductase M2 pseudogene 3
Sequences
M14223 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:10133 Ceci JD, et al., Genomics. 1989 Nov;5(4):699-709
Notes: The RFLV fragments of 15, 2.1, and 1.2 kb in M.spretus have been mapped to chromosomes 7, 12 and 13 respectively.
Endonuclease Gene Allele Fragments Strains
TaqI Rrm2-ps1 b 4.6,2.8,2.5,2.3,1.7,1.0,0.8,0.7,0.6,0.5kb C57BL/6J
s 15,3.1,2.8,2.5,2.1,1.9,1.2,1.0,0.7,0.6,0.5kb M. spretus
J:10344 Justice MJ, et al., Genomics. 1990 Feb;6(2):341-51
Endonuclease Gene Allele Fragments Strains
TaqI Rrm2-ps3 b 4.6,2.8,2.5,2.3,1.7,1.0,0.8,0.7,0.6,0.5kb C57BL/6J
s 15.5,3.1,2.8,2.5,2.1,1.9,1.2,1.0,0.7,0.6,0.5kb M. spretus
References
J:8537 Thelander L, et al., Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase. Mol Cell Biol. 1986 Oct;6(10):3433-42
J:8879 Yang-Feng TL, et al., Ribonucleotide reductase M2 subunit sequences mapped to four different chromosomal sites in humans and mice: functional locus identified by its amplification in hydroxyurea-resistant cell lines. Genomics. 1987 Sep;1(1):77-86
J:10133 Ceci JD, et al., A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes. Genomics. 1989 Nov;5(4):699-709
J:10344 Justice MJ, et al., A molecular genetic linkage map of mouse chromosome 13 anchored by the beige (bg) and satin (sa) loci. Genomics. 1990 Feb;6(2):341-51
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
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