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IV92 Probe Detail
Nucleotide
Probe/Clone
  • Name
    IV92
  • Sequence Type
    cDNA
  • ID
    MGI:12220
  • Region Covered
    encodes an Igh-VJ558 gene segment, Igh-D, Igh-J segments and the C1 exon of the Igh-4 gene segment
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    600 bp
Source
  • Species
    mouse, laboratory
  • Cell Line
    hybridoma cell line G8Ca1.7
Genes
Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker)
Igh-D immunoglobulin heavy chain diversity region
Igh-J immunoglobulin heavy chain, joining region
Igh-VJ558 immunoglobulin heavy chain (J558 family)
Polymorphisms
J:7120 Schiff C, et al., Nucleic Acids Res. 1983 Jun 25;11(12):4007-17
Notes: A PstI fragment of ~230 bp derived from the variable region of IV92 was isolated and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
BglII Igh-VJ558 a 20,12,8.5,5.5,4.2,3.9kb BALB/c
b 13,11.5,9,6.5,5.3,4.2, 3.9kb C57BL/6
c 15,10.5,8.5,5.5,4.2,3.9kb DBA/2
EcoRI Igh-VJ558 a 7.5,7.0,4.3,3.0kb BALB/c, DBA/2
b 9.4,7.2,4.5kb C57BL/6
References
J:7120 Schiff C, et al., Immunoglobulin diversity: analysis of the germ-line VH gene repertoire of the murine anti-GAT response. Nucleic Acids Res. 1983 Jun 25;11(12):4007-17
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory