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pGUS-1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pGUS-1
  • Sequence Type
    cDNA
  • ID
    MGI:12072
  • Region Covered
    encodes most of the coding region (5' end abbreviated)
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    1.5kb
Source
  • Species
    mouse, laboratory
  • Strain
    DBA/LiHa
  • Tissue
    kidney
  • Tissue Description
    androgen treated kidney
Genes
Gusb glucuronidase, beta
Sequences
J03035 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
J03047 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7396 Palmer R, et al., Proc Natl Acad Sci U S A. 1983 Dec;80(24):7596-600
Endonuclease Gene Allele Fragments Strains
HindII Gusb a not given DBA/LiHa-Gusba
b not given C57BL/6J-Gusbb
J:8964 Gallagher PM, et al., Genomics. 1987 Oct;1(2):145-52
Endonuclease Gene Allele Fragments Strains
HindIII Gusb a 4.0kb A/J, BALB/cBy, LG/J, SEA/GnJ, SEC/1ReJ, SM/J
b 3.8kb 129P3/J, ABP/LeJ, AU/SsJ, BDP/J, BUB/BnJ, C57BL/6J, C57BL/10J, C57BLKS/J, C57BR/cdJ, C57L/J, C58/J, CE/J, DBA/1J, DBA/2DeJ, DBA/2J, DW/J, FS/EiJ, MA/MyJ, NZB/BlNJ, O20/J, P/J, PL/J, RF/J, RIII/J, SJL/J, ST/bJ, STS/A, STX/LeJ, SWR/J, WB/ReJ, YBR/Br
h 3.8kb AKR/FuRdA, AKR/J, C3H/HeJ, C3HeB/FeJ, CBA/CaJ, CBA/J
J:9505 Geissler EN, et al., Proc Natl Acad Sci U S A. 1988 Dec;85(24):9635-9
Notes: A 1.5kb PstI/HindIII fragment was used for Southern blot analysis.
Endonuclease Gene Allele Fragments Strains
EcoRI Gusb d not given M. m. domesticus
s not given M. spretus
J:9598 Mock BA, et al., J Immunol. 1989 Feb 15;142(4):1372-6
Notes: A 1.36 kb HindIII/PstI fragment of pGUS-1 was subcloned into pBR322 and used for Southern analysis.
Endonuclease Gene Allele Fragments Strains
BamHI Gusb b 16.5,9.1,1.9kb C57BL/6J
s 22.1,9.1,3.7kb M. spretus
J:9705 Birkenmeier EH, et al., J Clin Invest. 1989 Apr;83(4):1258-6
Endonuclease Gene Allele Fragments Strains
HindIII Gusb a not given MOR/Rk
b not given STOCK Gusbmps
J:9723 Hill RE, et al., Genes Dev. 1989 Jan;3(1):26-37
Endonuclease Gene Allele Fragments Strains
BamHI Gusb b 16.5,9.1,1.9kb C57BL/6J
s 22.1,9.1,3.7kb M. spretus
J:10663 Eicher EM, et al., Genetics. 1990 Jun;125(2):431-46
Endonuclease Gene Allele Fragments Strains
HindIII Gusb n 3.2kb NZB
s 3.6kb SM
J:10844 Seldin MF, et al., Cytogenet Cell Genet. 1990;54(1-2):68-70
Endonuclease Gene Allele Fragments Strains
BamHI Gusb c ~10.0,~8.0,~4.3kb M. spretus
d ~10.0,~8.0,~2.0kb C3H/HeJ-Faslgld/J
J:2070 Taketo M, et al., Mamm Genome. 1992;2(4):240-5
Endonuclease Gene Allele Fragments Strains
BamHI Gusb c 17.0,8.0,2.0,1.3kb C3H/HeJ
s 17.0,8.0,4.3kb M. spretus
J:15567 Warden CH, et al., Genomics. 1993 Nov;18(2):295-307
Endonuclease Gene Allele Fragments Strains
PstI Gusb b 6.0kb C57BL/6J
s 6.0,3.8kb M. spretus
References
J:7396 Palmer R, et al., Genetic control of levels of murine kidney glucuronidase mRNA in response to androgen. Proc Natl Acad Sci U S A. 1983 Dec;80(24):7596-600
J:8964 Gallagher PM, et al., DNA sequence variation within the beta-glucuronidase gene complex among inbred strains of mice. Genomics. 1987 Oct;1(2):145-52
J:9505 Geissler EN, et al., Genetic analysis of the dominant white-spotting (W) region on mouse chromosome 5: identification of cloned DNA markers near W. Proc Natl Acad Sci U S A. 1988 Dec;85(24):9635-9
J:19331 Gallagher PM, et al., The complete nucleotide sequence of murine beta-glucuronidase mRNA and its deduced polypeptide. Genomics. 1988 Apr;2(3):215-9
J:9598 Mock BA, et al., The murine Il-6 gene maps to the proximal region of chromosome 5. J Immunol. 1989 Feb 15;142(4):1372-6
J:9705 Birkenmeier EH, et al., Murine mucopolysaccharidosis type VII. Characterization of a mouse with beta-glucuronidase deficiency. J Clin Invest. 1989 Apr;83(4):1258-6
J:9723 Hill RE, et al., A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. Genes Dev. 1989 Jan;3(1):26-37
J:10663 Eicher EM, et al., The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics. 1990 Jun;125(2):431-46
J:10844 Seldin MF, et al., Localization of mouse melanoma growth stimulatory activity gene (Mgsa) between Afp and Gus on chromosome 5 using interspecific backcross mice. Cytogenet Cell Genet. 1990;54(1-2):68-70
J:2070 Taketo M, et al., Mapping of recombinant retrovirus integration sites that cause expression of the viral genome in murine embryonal carcinoma cells. Mamm Genome. 1992;2(4):240-5
J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
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