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pMC4/7 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pMC4/7
  • Sequence Type
    cDNA
  • ID
    MGI:11993
  • Region Covered
    encodes 3' half of coding region and untranslated sequences, 3' half of [a] chain and almost entire length of the [g] chain
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    1.9kb
Source
  • Species
    mouse, laboratory
  • Strain
    B10.W7R
  • Tissue
    liver
Genes
C4b complement C4B (Chido blood group)
Polymorphisms
J:15369 Tosi M, et al., Philos Trans R Soc Lond B Biol Sci. 1984 Sep 6;306(1129):389-94
Notes: A 3'-PstI fragment was isolated from pMC4/7 and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
HindIII C4b a ~20,~15,~9,4.6kb B10.W7R
b ~20,4.6kb B10.HTT-H2t3
J:7795 Levi-Strauss M, et al., Proc Natl Acad Sci U S A. 1985 Mar;82(6):1746-50
Notes: A 3' PstI fragment was isolated and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
HindIII C4b a ~20,4.6kb B10.HTT-H2t3, B10.M-H2f/Sn, B10.S-H2t2/(7R), B10.S-H2t4/(9R)/J
b 9,4.6kb C57BL/10
C ~20,15,9,4.6kb B10.BUA1, B10.KPB128, B10.W7R
J:7816 Golubic M, et al., Immunogenetics. 1985;21(3):247-56
Endonuclease Gene Allele Fragments Strains
BamHI C4b a multiple B10.BR-H2k, B10.D2-H2d, B10.KPB68, BRU382, C3.t6, C3.tw5, C57BL/10Sn, CRO435, CRO437, EDY589, GPC183, GPC882, ISL33, LRA410, MOY336, MSW251, STOCK tLub1, STOCK tLub4, STOCK tLub9
b multiple B10.CAS2, BNK266, BNK761, BRW942, C3.t0, C3.tw73, C3H-tw2, ERP1465, LGN925, OBL984, PLD826, ROD1455
c multiple STOCK tLub7
d multiple C3.t12
BstEII C4b a multiple B10.BR-H2k2 H2-T18a/SgSnJ, B10.CAS2, B10.D2-H2d, B10.KPB68, BNK266, BNK761, BRU382, BRW942, C3.t6, C3.t12, C3.tw5, C3.tw73, C57BL/10Sn, CRO435, CRO437, EDY589, ERP1465, GPC183, ISL33, LGN925, LRA410, MOY336, MSW251, OBL984, PLD826, ROD1455, STOCK tLub1, STOCK tLub4, STOCK tLub7, STOCK tLub9
b multiple GPC882
c multiple C3H-tw2, STOCK t0
EcoRI C4b a multiple B10.KPB68, BRW942, C3.t6, C3.t12, C3.tw73, CRO435, EDY589, LRA410, MOY336, STOCK tLub1, STOCK tLub9
b multiple B10.BR-H2k2 H2-T18a/SgSnJ, B10.CAS2, B10.D2-H2d, BNK266, BNK761, BRU382, C3.t0, C3.tw5, C3H-tw2, ERP1465, GPC183, ISL33, LGN925, MSW251, OBL984, PLD826, ROD1455, STOCK tLub4
c multiple GPC882
d not specified C57BL/10Sn, STOCK tLub7
HindIII C4b a multiple B10.KPB68, C3.t6, EDY589, LRA410, MOY336, STOCK tLub1, STOCK tLub9
b multiple B10.BR-H2k2 H2-T18a/SgSnJ, BNK266, BNK761, BRU382, BRW942, C3.tw73, ERP1465, LGN925, MSW251, OBL984, PLD826, ROD1455
c multiple CRO435
d multiple C3.t0, C3H-tw2
e multiple GPC882
f multiple B10.D2-H2d, ISL33
g multiple C3.t12
h multiple CRO437
i multiple STOCK tLub4
j multiple C57BL/10Sn
k multiple B10.CAS2
l multiple C3.tw5, GPC183, STOCK tLub7
SacI C4b a multiple B10.BR-H2k2 H2-T18a/SgSnJ, B10.CAS2, B10.D2-H2d, B10.KPB68, BNK266, BNK761, BRU382, BRW942, C3.t6, C3.t12, C3.tw5, C3.tw73, C57BL/10Sn, CRO435, CRO437, EDY589, ERP1465, GPC183, LGN925, LRA410, MOY336, MSW251, OBL984, PLD826, ROD1455, STOCK tLub1, STOCK tLub4, STOCK tLub7, STOCK tLub9
b multiple GPC882
c multiple C3.t0, C3H-tw2
d multiple ISL33
XbaI C4b a multiple B10.BR-H2k2 H2-T18a/SgSnJ, B10.CAS2, B10.D2-H2d, B10.KPB68, BNK266, BNK761, BRU382, BRW942, C3.t6, C3.t12, C3.tw5, C3.tw73, C57BL/10Sn, CRO435, CRO437, EDY589, ERP1465, GPC183, ISL33, LGN925, LRA410, MOY336, MSW251, OBL984, PLD826, ROD1455, STOCK tLub1, STOCK tLub4, STOCK tLub7, STOCK tLub9
b multiple GPC882
c multiple C3.t0, C3H-tw2
J:10135 Vincek V, et al., Genomics. 1989 Nov;5(4):773-86
Endonuclease Gene Allele Fragments Strains
Not Specified C4b b not given C57BL/6J
d not given DBA/2
Not Specified C4b b not given C57BL/6J
h not given C3H/HeJ
References
J:15369 Tosi M, et al., Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component. Philos Trans R Soc Lond B Biol Sci. 1984 Sep 6;306(1129):389-94
J:7795 Levi-Strauss M, et al., Multiple duplications of complement C4 gene correlate with H-2-controlled testosterone-independent expression of its sex-limited isoform, C4-Slp. Proc Natl Acad Sci U S A. 1985 Mar;82(6):1746-50
J:7816 Golubic M, et al., Restriction fragment length polymorphism of C4 genes in mice with t chromosomes. Immunogenetics. 1985;21(3):247-56
J:10135 Vincek V, et al., Linkage map of mouse chromosome 17: localization of 27 new DNA markers. Genomics. 1989 Nov;5(4):773-86

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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory