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pM-alpha-Acr2 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pM-alpha-Acr2
  • Sequence Type
    cDNA
  • ID
    MGI:11940
  • Region Covered
    coding region & 3' untranslated sequence
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    1067 bp
  • Synonyms
    pM-alpha-ACr1
Source
  • Species
    mouse, laboratory
  • Age
    postnatal day 5-10.0
  • Tissue
    lens
Genes
Cryaa crystallin, alpha A
Polymorphisms
J:7973 Skow LC, et al., Genetics. 1985 Aug;110(4):723-32
Endonuclease Gene Allele Fragments Strains
BamHI Cryaa a 9.5,3.8,1.0kb 129P3/J, AU/SsJ, BALB/cJ, BUB/BnJ, DBA/2J, MA/MyJ, NZB/BlNJ, RIIIS/J, SEC/1ReJ, SWR/J, YBR/Ki
b 9.5,3.8,1.0kb A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/10Sn, C57BR/cdJ, C57L/J, C58/J, CBA/J, CE/J, SM/J
c 9.8,3.6,1.0kb PL/J
d 9.8,3.6,1.0kb MOLD/RkJ
e 12.5,3.6,1.0kb CASA/RkJ
f 8.0,3.8,1.0kb SJL/J
BclI Cryaa a 5.2,4.4kb 129P3/J, AU/SsJ, BALB/cJ, BUB/BnJ, DBA/2J, MA/MyJ, NZB/BlNJ, RIIIS/J, SEC/1ReJ, SWR/J, YBR/Ki
b 5.4,4.4kb A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/10Sn, C57BR/cdJ, C57L/J, C58/J, CBA/J, CE/J, SM/J
c 5.4kb PL/J
d 5.4kb MOLD/RkJ
e 5.4kb CASA/RkJ
f 7.5,4.4kb SJL/J
BglII Cryaa a 13.0kb 129P3/J, AU/SsJ, BALB/cJ, BUB/BnJ, DBA/2J, MA/MyJ, NZB/BlNJ, RIIIS/J, SEC/1ReJ, SWR/J, YBR/Ki
b 13.0kb A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/10Sn, C57BR/cdJ, C57L/J, C58/J, CBA/J, CE/J, SM/J
c 10.3,2.7kb PL/J
d 11.0,2.7kb MOLD/RkJ
e 11.0,2.7kb CASA/RkJ
f 8.0kb SJL/J
HincII Cryaa a 12.0kb 129P3/J, AU/SsJ, BALB/cJ, BUB/BnJ, DBA/2J, MA/MyJ, NZB/BlNJ, RIIIS/J, SEC/1ReJ, SWR/J, YBR/Ki
b 10.5kb A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/10Sn, C57BR/cdJ, C57L/J, C58/J, CBA/J, CE/J, SM/J
c 10.5kb PL/J
d 10.5kb MOLD/RkJ
e 10.5kb CASA/RkJ
f 9.0kb SJL/J
HindIII Cryaa a 13.0,6.0kb 129P3/J, AU/SsJ, BALB/cJ, BUB/BnJ, DBA/2J, MA/MyJ, NZB/BlNJ, RIIIS/J, SEC/1ReJ, SWR/J, YBR/Ki
b 13.0,6.0kb A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/10Sn, C57BR/cdJ, C57L/J, C58/J, CBA/J, CE/J, SM/J
c 13.0,5.9kb PL/J
d 13.0,5.9kb MOLD/RkJ
e 8.5,5.9kb CASA/RkJ
f 10.5,6.0kb SJL/J
MspI Cryaa a 2.0,1.4,1.3kb 129P3/J, AU/SsJ, BALB/cJ, BUB/BnJ, DBA/2J, MA/MyJ, NZB/BlNJ, RIIIS/J, SEC/1ReJ, SWR/J, YBR/Ki
b 2.0,1.4,1.1kb A/J, AKR/J, C3H/HeJ, C57BL/6J, C57BL/10Sn, C57BR/cdJ, C57L/J, C58/J, CBA/J, CE/J, SM/J
c 2.0,1.4,1.2kb PL/J
d 2.0,1.4,1.2kb MOLD/RkJ
e 2.0,1.4,1.2kb CASA/RkJ
f 2.0,1.4.1.1kb SJL/J
J:8922 Bucan M, et al., Genes Dev. 1987 Jun;1(4):376-85
Endonuclease Gene Allele Fragments Strains
Not Specified Cryaa b not given C57BL/6J
d not given DBA/2J
J:3040 Hoopes CW, et al., Genomics. 1992 Nov;14(3):611-7
Endonuclease Gene Allele Fragments Strains
PvuII Cryaa c 11.0kb C3H/HeJ
s 8.5kb M. spretus
References
J:6970 King CR, et al., alpha A-crystallin messenger RNA of the mouse lens: more noncoding than coding sequences. Science. 1982 Feb 19;215(4535):985-7
J:7973 Skow LC, et al., The locus encoding alpha A-crystallin is closely linked to H-2K on mouse chromosome 17. Genetics. 1985 Aug;110(4):723-32
J:8922 Bucan M, et al., Deletion and duplication of DNA sequences is associated with the embryonic lethal phenotype of the t9 complementation group of the mouse t complex. Genes Dev. 1987 Jun;1(4):376-85
J:9014 Quinlan P, et al., The mouse eye lens obsolescence (Elo) mutant: studies on crystallin gene expression and linkage analysis between the mutant locus and the gamma-crystallin genes. Genes Dev. 1987 Sep;1(7):637-44
J:3040 Hoopes CW, et al., Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma. Genomics. 1992 Nov;14(3):611-7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory