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pM-beta-3 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pM-beta-3
  • Sequence Type
    cDNA
  • ID
    MGI:11938
  • Region Covered
    all of coding region, 3' and 5' flanking sequences
  • Child Clones
    Ifb frag, pGEM-1-beta-3
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    680 bp
  • Synonyms
    pMbeta3
Source
  • Species
    mouse, laboratory
  • Tissue
    fibroblast
  • Tissue Description
    virus-induced
  • Cell Line
    L-Cell
Genes
Ifnb1 interferon beta 1, fibroblast
Sequences
K00020 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:7993 Dandoy F, et al., J Virol. 1985 Oct;56(1):216-20
Endonuclease Gene Allele Fragments Strains
EcoRI Ifnb1 b 2.8kb BALB/c, C57BL/6, DBA/2
s 2.9kb M. spretus
HindIII Ifnb1 b ~23kb BALB/c, C57BL/6, DBA/2
s ~16kb M. spretus
J:8569 Nadeau JH, et al., Genetics. 1986 Dec;114(4):1239-55
Notes: A PstI/BglII fragment of pM3 was used as the hybridization probe.
Endonuclease Gene Allele Fragments Strains
HindIII Ifnb1 a 14.0kb AKR/J
s 26.0kb M. spretus
J:9879 Dandoy F, et al., Genomics. 1989 May;4(4):546-51
Endonuclease Gene Allele Fragments Strains
HindIII Ifnb1 d ~15kb DBA/2Ico
s ~23kb M. spretus
J:14725 Vigon I, et al., Oncogene. 1993 Oct;8(10):2607-15
Endonuclease Gene Allele Fragments Strains
BamHI Ifnb1 b 9.0kb C57BL/6
s 5.6kb SEG/Pas
References
J:7139 Higashi Y, et al., Structure and expression of a cloned cDNA for mouse interferon-beta. J Biol Chem. 1983 Aug 10;258(15):9522-9
J:7993 Dandoy F, et al., Segregation of restriction fragment length polymorphism in an interspecies cross of laboratory and wild mice indicates tight linkage of the murine IFN-beta gene to the murine IFN-alpha genes. J Virol. 1985 Oct;56(1):216-20
J:8569 Nadeau JH, et al., Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4. Genetics. 1986 Dec;114(4):1239-55
J:9879 Dandoy F, et al., Linkage analysis of the murine mos proto-oncogene on chromosome 4. Genomics. 1989 May;4(4):546-51
J:14725 Vigon I, et al., Characterization of the murine Mpl proto-oncogene, a member of the hematopoietic cytokine receptor family: molecular cloning, chromosomal location and evidence for a function in cell growth. Oncogene. 1993 Oct;8(10):2607-15
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory