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pRT57 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pRT57
  • Sequence Type
    cDNA
  • ID
    MGI:11891
  • Vector Type
    Plasmid
  • Insert Site
    PstI
  • Insert Size
    4.5kb
  • Note
    RFLPs were detected with various combinations of endonucleases BamHI, EcoRI, HindIII, PstI, MspI, XbaI, and SstI.
Source
  • Species
    rat
Genes
Tg thyroglobulin
Polymorphisms
J:8652 Taylor BA, et al., Proc Natl Acad Sci U S A. 1987 Apr;84(7):1986-90
Notes: Additional restriction fragments are observed on Southern blots, only variant fragments are listed in RFLP tables.
Endonuclease Gene Allele Fragments Strains
HindIII Tg a 15,4.5,3.0kb A/J, AKR/J, RIIIS/J, SWR/J
b 15,4.5,3.0kb 129P3/J, BUB/BnJ, C57BL/6J, C57BR/cdJ, C57L/J, C58/J, DBA/2J, I/LnJ, LG/J, MA/MyJ, NZB/BlNJ, SF/CamEiJ, SJL/J, ST/bJ
c 17,7.5kb BALB/cBy, C3H/HeJ, CBA/J, CE/J
d 15,7.5kb IS/CamEi
e 17,4.5,3.0kb P/J
f 15,7.5kb MOLF/EiJ
g 15,7.5kb CAST/EiJ
p 15,4.5,3.0kb PERA/EiJ, PL/J
PvuII Tg a 3.0kb A/J, AKR/J, RIIIS/J, SWR/J
b 2.5kb 129P3/J, BUB/BnJ, C57BL/6J, C57BR/cdJ, C57L/J, C58/J, DBA/2J, I/LnJ, LG/J, MA/MyJ, NZB/BlNJ, SF/CamEiJ, SJL/J, ST/bJ
c 2.5kb BALB/cBy, C3H/HeJ, CBA/J, CE/J
d 2.5kb IS/CamEi
e 2.5kb P/J
f 3.5,2.5kb MOLF/EiJ
g 4.0,2.5kb CAST/EiJ
p 2.5kb PERA/EiJ, PL/J
TaqI Tg a 5.5kb A/J, AKR/J, RIIIS/J, SWR/J
b 4.4kb 129P3/J, BUB/BnJ, C57BL/6J, C57BR/cdJ, C57L/J, C58/J, DBA/2J, I/LnJ, LG/J, MA/MyJ, NZB/BlNJ, SF/CamEiJ, SJL/J, ST/bJ
c 3.5kb BALB/cBy, C3H/HeJ, CBA/J, CE/J
d 5.5kb IS/CamEi
e 4.4kb P/J
f 4.4kb MOLF/EiJ
g 5.0kb CAST/EiJ
p 5.5kb PERA/EiJ, PL/J
J:10663 Eicher EM, et al., Genetics. 1990 Jun;125(2):431-46
Endonuclease Gene Allele Fragments Strains
TaqI Tg n 4.8kb NZB
s 6.6kb SM
J:457 Eicher EM, et al., Mamm Genome. 1991;1(1):57-8
Endonuclease Gene Allele Fragments Strains
TaqI Tg c 3.5kb BALB/cJ
g 5.0kb CAST/EiJ
J:11120 Siracusa LD, et al., Genetics. 1991 Jan;127(1):169-79
Notes: The 2.9 and 2.1kb M.spretus bands were not visible on all Southerns.
Endonuclease Gene Allele Fragments Strains
BamHI Tg b ~16.0,9.3,8.1,6.5,5.8,4.0,3.6,3.4,2.0kb C57BL/6J
s ~14.0,8.1,6.5,5.8,3.6,3.4,2.9,2.1kb M. spretus
References
J:8652 Taylor BA, et al., The congenital goiter mutation is linked to the thyroglobulin gene in the mouse. Proc Natl Acad Sci U S A. 1987 Apr;84(7):1986-90
J:10380 Adolph S, et al., Fine localization of genes on distal murine chromosome 15. Cytogenet Cell Genet. 1989;52(3-4):177-9
J:10663 Eicher EM, et al., The NXSM recombinant inbred strains of mice: genetic profile for 58 loci including the Mtv proviral loci. Genetics. 1990 Jun;125(2):431-46
J:457 Eicher EM, et al., Growth hormone receptor (Ghr) and hemoglobin alpha-chain pseudogene 3 (Hba-ps3) map proximal to the myelocytomatosis oncogene (Myc) on mouse chromosome 15. Mamm Genome. 1991;1(1):57-8
J:11120 Siracusa LD, et al., Identification and applications of repetitive probes for gene mapping in the mouse. Genetics. 1991 Jan;127(1):169-79
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05/07/2024
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