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M19DB2.HE Probe Detail
Nucleotide
Probe/Clone
  • Name
    M19DB2.HE
  • Sequence Type
    genomic
  • ID
    MGI:11544
  • Region Covered
    encodes D[b]2-1 and J[b]2-1
  • Parent Clone
    2.3W7
  • Vector Type
    Phage
  • Insert Site
    EcoRI/HindIII
  • Insert Size
    ~2.4 kb
  • Synonyms
    D-beta-2 probe, Probe E
Source
  • Species
    mouse, laboratory
  • Strain
    B10.WR7-H2
  • Tissue
    liver
Genes
Tcrb-D T cell receptor beta, D region
Tcrb-J T cell receptor beta, joining region
Polymorphisms
J:7920 Kotzin BL, et al., Science. 1985 Jul 12;229(4709):167-71
Endonuclease Gene Allele Fragments Strains
BamHI Tcrb-D a ~8kb SJL
c ~13kb BALB/c
n - NZW
EcoRI Tcrb-D a ~5kb SJL
c ~5kb BALB/c
n - NZW
PvuII Tcrb-D a ~8,~1kb SJL
c ~7,~1kb BALB/c
n - NZW
References
J:7596 Siu G, et al., The structure, rearrangement and expression of D beta gene segments of the murine T-cell antigen receptor. Nature. 1984 Sep 27-Oct 3;311(5984):344-50
J:7753 Kronenberg M, et al., Rearrangement and transcription of the beta-chain genes of the T-cell antigen receptor in different types of murine lymphocytes. Nature. 1985 Feb 21-27;313(6004):647-53
J:7920 Kotzin BL, et al., A large deletion within the T-cell receptor beta-chain gene complex in New Zealand white mice. Science. 1985 Jul 12;229(4709):167-71
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory