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pXM-6 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pXM-6
  • Sequence Type
    cDNA
  • ID
    MGI:11493
  • Parent Clone
    Il-6 cDNA-1
  • Vector Type
    Phage
  • Insert Size
    1010bp
Source
  • Species
    mouse, laboratory
  • Tissue
    stromal cells
  • Cell Line
    W20, Il-1 stimulated
Genes
Il6 interleukin 6
Polymorphisms
J:9598 Mock BA, et al., J Immunol. 1989 Feb 15;142(4):1372-6
Notes: Using a 950 bp XhoI fragment isolated from pXM-6 for a probe, a number of strains were subjected to Southern analysis and were determined to be nonpolymorphic (~20 restriction enzymes utilized).
Endonuclease Gene Allele Fragments Strains
BamHI Il6 b 10.2,5.1kb C57BL/6J
s 10.2,4.9kb M. spretus
J:9723 Hill RE, et al., Genes Dev. 1989 Jan;3(1):26-37
Endonuclease Gene Allele Fragments Strains
BamHI Il6 b 10.2,5.2kb C57BL/6J
s 10.2,4.9kb M. spretus
J:1673 Chin H, et al., Genomics. 1992 Aug;13(4):1325-7
Endonuclease Gene Allele Fragments Strains
PstI Il6 m not given M. m. musculus
n not given C58/J, NFS/N
J:14687 Harada N, et al., J Immunol. 1993 Sep 15;151(6):3111-8
Endonuclease Gene Allele Fragments Strains
Not Specified Il6 b not given C57BL/6J
s not given M. spretus
References
J:9598 Mock BA, et al., The murine Il-6 gene maps to the proximal region of chromosome 5. J Immunol. 1989 Feb 15;142(4):1372-6
J:9723 Hill RE, et al., A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1. Genes Dev. 1989 Jan;3(1):26-37
J:1673 Chin H, et al., The gene for the dihydropyridine-sensitive calcium channel alpha 2 subunit (CCHL2A) maps to the proximal region of mouse chromosome 5. Genomics. 1992 Aug;13(4):1325-7
J:14687 Harada N, et al., Expression cloning of a cDNA encoding a novel murine B cell activation marker. Homology to human CD38. J Immunol. 1993 Sep 15;151(6):3111-8
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory