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MMTV cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    MMTV cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:10563
  • Region Covered
    full length MTV
  • Insert Size
    10.0kb
Source
  • Species
    virus
Genes
Mtv1 mammary tumor virus locus 1
Mtv11 mammary tumor virus locus 11
Mtv13 mammary tumor virus locus 13
Mtv14 mammary tumor virus locus 14
Mtv17 mammary tumor virus locus 17
Mtv2 mammary tumor virus locus 2
Mtv3 mammary tumor virus locus 3
Mtv6 mammary tumor virus locus 6
Mtv7 mammary tumor virus locus 7
Mtv8 mammary tumor virus locus 8
Mtv9 mammary tumor virus locus 9
Polymorphisms
J:6673 Traina VL, et al., J Virol. 1981 Dec;40(3):735-44
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv1 b absent C57BL/6J
d 16.7kb C3H/HeJ, DBA/2J
EcoRI Mtv9 b 10.0,7.8kb C57BL/6J
d absent C3H/HeJ, DBA/2J
Not Specified Mtv6 b absent C57BL/6J
d 6.5,4.5kb C3H/HeJ, DBA/2J
Not Specified Mtv7 b absent C57BL/6J
d 11.7,10.0kb C3H/HeJ, DBA/2J
Not Specified Mtv11 b absent C57BL/6J
d 5.8kb C3H/HeJ, DBA/2J
Not Specified Mtv13 b absent C57BL/6J
d 15.0kb DBA/2J
Not Specified Mtv14 b absent C57BL/6J
d 1.7kb C3H/HeJ, DBA/2J
J:7326 MacInnes JI, et al., Virology. 1984 Jan 15;132(1):12-25
Endonuclease Gene Allele Fragments Strains
BamHI Mtv1 a 8.0,4.4kb DBA/2J
b absent GR/Imr, NFS/N
BamHI Mtv2 a not given GR/Imr
b absent DBA/2J, NFS/N
BamHI Mtv3 a 11.4kb GR/Imr
b absent DBA/2J, NFS/N
BamHI Mtv6 a not given DBA/2J
b not given GR/Imr, NFS/N
BamHI Mtv11 a 23.4,4.2kb DBA/2J
b absent GR/Imr, NFS/N
BamHI Mtv13 a 17.2,4.4kb DBA/2J, NFS/N
b absent GR/Imr
EcoRI Mtv1 a 6.5,4.5kb DBA/2J
b absent GR/Imr, NFS/N
EcoRI Mtv2 a 17.4,6.9,0.9kb GR/Imr
b absent DBA/2J, NFS/N
EcoRI Mtv3 a 11.4,7.0kb GR/Imr
b absent DBA/2J, NFS/N
EcoRI Mtv6 a 16.7kb DBA/2J
b absent GR/Imr, NFS/N
EcoRI Mtv11 a 15.0,5.8kb DBA/2J
b absent GR/Imr, NFS/N
EcoRI Mtv13 a 9.0,5.8kb DBA/2J, NFS/N
b absent GR/Imr
J:8083 Michalides R, et al., Virology. 1985 Apr 30;142(2):278-90
Notes: MMTV probes recognize multiple Mtv-loci, therefore additional fragments are observed.
Endonuclease Gene Allele Fragments Strains
EcoRI Mtv3 a 21,7,1kb STS/A
b absent BALB/cHeA
EcoRI Mtv6 a 16.7kb BALB/cHeA
b absent STS/A
EcoRI Mtv7 a 16.7,13.0kb STS/A
b absent BALB/cHeA
EcoRI Mtv8 a 8.5,6.7kb BALB/cHeA, STS/A
EcoRI Mtv9 a 10.0,7.8kb BALB/cHeA
b absent STS/A
EcoRI Mtv17 a 10.6,8.7kb STS/A
b absent BALB/cHeA
References
J:6673 Traina VL, et al., Genetic mapping of endogenous mouse mammary tumor viruses: locus characterization, segregation, and chromosomal distribution. J Virol. 1981 Dec;40(3):735-44
J:7326 MacInnes JI, et al., Characterization and chromosomal location of endogenous mouse mammary tumor virus loci in GR, NFS, and DBA mice. Virology. 1984 Jan 15;132(1):12-25
J:8083 Michalides R, et al., Characterization and chromosomal distribution of endogenous mouse mammary tumor viruses of European mouse strains STS/A and GR/A. Virology. 1985 Apr 30;142(2):278-90
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory