Pax-3 cDNA Probe Detail MGI Mouse MGI:10380

Pax-3 cDNA Probe Detail

Name

Pax-3 cDNA
Sequence Type

cDNA
ID

MGI:10380
Region Covered

5' end of Pax-3 corresponding to positions +84 to +1078
Vector Type

Plasmid
Insert Size

~1.0kb
Note

This clone is derived from a gene that produces alternate transcripts.

Species

mouse, laboratory
Tissue

embryo
Cell Line

embryonal carcinoma cell line P19

Pax3

paired box 3

J:2944 Epstein DJ, et al., Cell. 1991 Nov 15;67(4):767-74

Endonuclease	Gene	Allele	Fragments	Strains
TaqI	Pax3	a	4.4,2.8,2.5,2.1,1.5,0.6kb	101/Orr
		c	4.4,3.1,2.5,2.1,1.5,0.6kb	C3H/HeJ
		s	5.0,2.8,2.5,2.1,1.5kb	STOCK Pax3^Sp-2H

J:2895 Mancino F, et al., Cytogenet Cell Genet. 1992;61(2):143-5

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	Pax3	a	6.4kb	CBA/J
BamHI	Pax3	b	2.6,3.8,8.0kb	C57BL/6J-Pax3^Sp/J

J:2944 Epstein DJ, et al., Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell. 1991 Nov 15;67(4):767-74

J:2895 Mancino F, et al., Segregation analysis reveals tight genetic linkage between the spontaneously arising neural tube defect gene splotch (Sp) and Pax-3 in an intraspecific mouse backcross. Cytogenet Cell Genet. 1992;61(2):143-5

J:36547 Vogan KJ, et al., An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity. Mol Cell Biol. 1996 Dec;16(12):6677-86

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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