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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tgfbi
transforming growth factor, beta induced
MGI:99959
27 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tgfbiem1Yaou/Tgfbi+
involves: C57BL/6NCr
corneal opacity J:285437
Tgfbiem1Yaou/Tgfbiem1Yaou
involves: C57BL/6NCr
abnormal cornea morphology J:285437
abnormal corneal stroma morphology J:285437
corneal opacity J:285437
delayed wound healing J:285437
Tgfbitm1.1Nap/Tgfbitm1.1Nap
B6N.129S(FVB)-Tgfbitm1.1Nap
abnormal retina inner nuclear layer thickness J:230754
decreased retina apoptosis J:230754
normal neoplasm J:230754
normal vision/eye phenotype J:230754
Tgfbitm1Jwu/Tgfbitm1Jwu
B6.129-Tgfbitm1Jwu
abnormal pancreatic islet morphology J:213611
decreased insulin secretion J:213611
normal endocrine/exocrine gland phenotype J:213611
normal growth/size/body region phenotype J:213611
increased pancreatic beta cell apoptosis J:213611
increased susceptibility to non-insulin-dependent diabetes J:213611
Tgfbitm1Jwu/Tgfbitm1Jwu
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal pancreatic beta cell physiology J:213611
Tgfbitm1Zhao/Tgfbitm1Zhao
involves: 129 * C57BL/6J
abnormal cell nucleus morphology J:143036
abnormal chromosome morphology J:143036
decreased body weight J:143036
enlarged spleen J:143036
increased B cell number J:143036
increased incidence of tumors by chemical induction J:143036
increased lung adenocarcinoma incidence J:143036
increased lymphoma incidence J:143036
increased malignant tumor incidence J:143036
increased tumor incidence J:143036
postnatal growth retardation J:143036
premature death J:143036

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory