Lamc2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Lamc2
laminin, gamma 2
MGI:99913

27 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lamc2^jeb/Lamc2^jeb 129X1/SvJ-Lamc2^jeb	abnormal basal lamina morphology	J:158873
	abnormal incisor morphology	J:158873
	abnormal pinna cartilage morphology	J:158873
	abnormal skin morphology	J:158873
	acanthosis	J:158873
	blistering	J:158873
	decreased airway resistance	J:158873
	decreased bone mineral content	J:158873
	decreased bone mineral density	J:158873
	decreased lung elastance	J:158873
	decreased skin tensile strength	J:158873
	dermal-epidermal separation	J:158873
	ear inflammation	J:158873
	enamel pits	J:158873
	epidermal hyperplasia	J:158873
	orthokeratosis	J:158873
	reddish skin	J:158873
	respiratory distress	J:158873
	skin detachment	J:158873
	spontaneous skin ulceration	J:158873
	ulcerated autopod	J:158873
Lamc2^jeb/Lamc2^jeb B6.129X1-Lamc2^jeb/Dcr	abnormal epidermal-dermal junction morphology	J:186910
	decreased skin tensile strength	J:186910
	dermal-epidermal separation	J:186910
Lamc2^jeb/Lamc2^tm1Uit (129X1/SvJ-Lamc2^jeb x B6.Cg-Lamc2^tm1Uit)F1	blistering	J:158873
	dermal-epidermal separation	J:158873
Lamc2^tm1Uit/Lamc2^tm1Uit involves: C57BL/6	abnormal digestive system morphology	J:85981
	abnormal kidney morphology	J:85981
	abnormal skin morphology	J:85981
	abnormal urinary bladder urothelium morphology	J:85981
	aphagia	J:85981
	blistering	J:85981
	dermal-epidermal separation	J:85981
	postnatal lethality, complete penetrance	J:85981

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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