129 phenotypes from 6 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Brd2em1(IMPC)Wtsi/Brd2+ C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg	abnormal auditory brainstem response	J:211773
	abnormal vertebral arch morphology	J:211773
	decreased CD8-positive, alpha-beta T cell number	J:211773
	increased CD4-positive, alpha-beta T cell number	J:211773
	increased mean corpuscular hemoglobin	J:211773
Brd2em1(IMPC)Wtsi/Brd2em1(IMPC)Wtsi C57BL/6N-Brd2em1(IMPC)Wtsi/WtsiIeg	abnormal adenohypophysis morphology	J:239583
	abnormal aortic valve morphology	J:239583
	abnormal brain artery topology	J:239583
	abnormal choroid plexus morphology	J:239583
	abnormal common carotid artery morphology	J:239583
	abnormal ductus venosus morphology	J:239583
	abnormal ductus venosus topology	J:239583
	abnormal external carotid artery origin	J:239583
	abnormal forebrain morphology	J:239583
	abnormal gallbladder morphology	J:239583
	abnormal hepatic portal vein connection	J:239583
	abnormal hypoglossal nerve topology	J:239583
	abnormal interatrial septum morphology	J:239583
	abnormal lung position or orientation	J:239583
	abnormal middle ear ossicle morphology	J:239583
	abnormal Mullerian duct topology	J:239583
	abnormal nasal septum morphology	J:239583
	abnormal olfactory nerve morphology	J:239583
	abnormal optic chiasm morphology	J:239583
	abnormal optic cup morphology	J:239583
	abnormal optic stalk morphology	J:239583
	abnormal pectinate muscle morphology	J:239583
	abnormal physiological umbilical hernia morphology	J:239583
	abnormal pineal gland morphology	J:239583
	abnormal pulmonary valve morphology	J:239583
	abnormal semilunar valve morphology	J:239583
	abnormal thymus topology	J:239583
	abnormal umbilical vein topology	J:239583
	abnormal vagus ganglion morphology	J:239583
	abnormal vertebral arch morphology	J:239583
	abnormal vertebral artery topology	J:239583
	abnormal vertebral body morphology	J:239583
	absent connection between subcutaneous lymph vessels and lymph sac	J:239583
	absent costovertebral joint	J:239583
	absent eye muscles	J:239583
	absent pectinate muscle	J:239583
	absent superior cervical ganglion	J:239583
	absent vagus nerve	J:239583
	absent vertebral arch	J:239583
	aorta coarctation	J:239583
	aphakia	J:239583
	artery stenosis	J:239583
	atrioventricular septal defect	J:239583
	basisphenoid bone foramen	J:239583
	blood in lymph vessels	J:239583
	common truncal valve	J:239583
	decreased rib number	J:239583
	dilated liver sinusoidal space	J:239583
	double outlet right ventricle	J:239583
	dual inferior vena cava	J:239583
	duplication of ductus venosus	J:239583
	enlarged brain ventricles	J:239583
	enlarged heart	J:239583
	exencephaly	J:239583
	fetal growth retardation	J:239583
	fusion of vertebral arches	J:239583
	hemorrhage	J:239583
	heterochrony	J:239583
	increased rib number	J:239583
	interrupted aortic arch, type b	J:239583
	muscular ventricular septal defect	J:239583
	myelocele	J:239583
	perimembraneous ventricular septal defect	J:239583
	persistent right dorsal aorta	J:239583
persistent trigeminal artery	J:239583
persistent truncus arteriosus	J:239583
preweaning lethality, complete penetrance	J:211773
reduced sympathetic cervical ganglion size	J:239583
retroesophageal right subclavian artery	J:239583
retropleural edema	J:239583
rib bifurcation	J:239583
rib fusion	J:239583
scoliosis	J:239583
small kidney	J:239583
small thymus	J:239583
small thyroid gland	J:239583
subcutaneous edema	J:239583
thin myocardium compact layer	J:239583
thoracoschisis	J:239583
transposition of great arteries	J:239583
Brd2Gt(RRE050)Byg/Brd2+ involves: 129P2/OlaHsd * C57BL/6J	abnormal embryo size	J:147040
	decreased cell proliferation	J:147040
Brd2Gt(RRE050)Byg/Brd2Gt(RRE050)Byg involves: 129P2/OlaHsd * C57BL/6J	abnormal cell cycle	J:147040
	abnormal cell death	J:147040
	abnormal neural tube closure	J:147040
	decreased cell proliferation	J:147040
	decreased embryo size	J:147040
	embryonic lethality during organogenesis, complete penetrance	J:147040
	increased embryonic tissue cell apoptosis	J:147040
Brd2Gt(RRT234)Byg/Brd2+ B6.129P2-Brd2Gt(RRT234)Byg	abnormal adipose tissue morphology	J:159964
	abnormal blood homeostasis	J:159964
	abnormal circulating lipid level	J:159964
	abnormal eating behavior	J:159964
	abnormal pancreatic islet morphology	J:159964
	abnormal respiratory quotient	J:159964
	decreased circulating glucose level	J:159964
	hepatic steatosis	J:159964
	improved glucose tolerance	J:159964
	increased basal metabolism	J:159964
	increased circulating adiponectin level	J:159964
	increased circulating cholesterol level	J:159964
	increased circulating glucagon level	J:159964
	increased circulating insulin level	J:159964
	increased circulating interleukin-1 beta level	J:159964
	increased circulating leptin level	J:159964
	increased circulating triglyceride level	J:159964
	increased circulating tumor necrosis factor level	J:159964
	increased epididymal fat pad weight	J:159964
	increased fat cell size	J:159964
	increased interscapular fat pad weight	J:159964
	increased pancreatic beta cell number	J:159964
	increased pancreatic islet number	J:159964
	increased total body fat amount	J:159964
	obese	J:159964
	pancreatic islet hyperplasia	J:159964
Brd2Gt(RRT234)Byg/Brd2Gt(RRT234)Byg B6.129P2-Brd2Gt(RRT234)Byg	perinatal lethality, incomplete penetrance	J:159964
	postnatal lethality, incomplete penetrance	J:159964
H2-Oa/Brd2Tg(otx2-lacZ)F5pImat/H2-Oa/Brd2Tg(otx2-lacZ)F5pImat involves: CD-1	abnormal cell cycle	J:188139
	abnormal craniofacial morphology	J:188139
	abnormal embryonic neuroepithelial layer differentiation	J:188139
	abnormal embryonic neuroepithelium morphology	J:188139
	abnormal neural tube morphology	J:188139
	embryonic growth retardation	J:188139
	embryonic lethality during organogenesis, complete penetrance	J:188139
	increased embryonic neuroepithelium apoptosis	J:188139
	increased embryonic neuroepithelium thickness	J:188139
H2-Oa/Brd2Tg(otx2-lacZ)F5pImat/H2-Oa/Brd2Tg(otx2-lacZ)F5pImat Tg(CAG-Brd2,-EGFP)#Imat/0 involves: CD-1	normal embryo phenotype	J:188139
H2-Oa/Brd2Tg(otx2-lacZ)F5pImat/H2-Oa/Brd2Tg(otx2-lacZ)F5pImat Tg(CAG-EGFP/Brd2)#Imat/0 involves: CD-1	no abnormal phenotype detected	J:188139