83 phenotypes from 9 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbx3em1(IMPC)Mbp/Tbx3+ C57BL/6NCrl-Tbx3em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal lymph node morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased locomotor activity	J:211773
	enlarged spleen	J:211773
	eye hemorrhage	J:211773
	increased circulating alkaline phosphatase level	J:211773
	microphthalmia	J:211773
Tbx3em1(IMPC)Mbp/Tbx3em1(IMPC)Mbp C57BL/6NCrl-Tbx3em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
Tbx3tm1.1(cre)Vmc/Tbx3+ involves: 129P2/OlaHsd * FVB/N * NMRI	no abnormal phenotype detected	J:154920
Tbx3tm1.1(cre)Vmc/Tbx3tm1.1(cre)Vmc involves: 129P2/OlaHsd * FVB	abnormal limb morphology	J:121230
	abnormal mammary gland development	J:121230
	abnormal sinoatrial node morphology	J:121230
	decreased sinoatrial node size	J:121230
	embryonic lethality during organogenesis, complete penetrance	J:121230
Tbx3tm1.1(cre)Vmc/Tbx3tm1.1(cre)Vmc involves: 129P2/OlaHsd * FVB/N * NMRI	abnormal palatal shelf fusion at midline	J:154920
	cleft secondary palate	J:154920
	lethality throughout fetal growth and development, complete penetrance	J:154920
Tbx3tm1.1Moon/Tbx3+ involves: 129 * C57BL/6 * SJL	irregular heartbeat	J:179977
	reduced female fertility	J:179977
	reduced male fertility	J:179977
Tbx3tm1.1Moon/Tbx3tm1.1Moon involves: 129 * C57BL/6 * SJL	abnormal heart development	J:179977
	embryonic lethality, incomplete penetrance	J:179977
Tbx3tm1.1Moon/Tbx3tm2Moon involves: 129 * C57BL/6 * SJL	abnormal cardiovascular development	J:179977
	abnormal limb morphology	J:179977
	atrioventricular block	J:179977
	decreased heart rate	J:179977
	normal embryo phenotype	J:179977
	embryonic lethality during organogenesis, incomplete penetrance	J:179977
	irregular heartbeat	J:179977
	lethality throughout fetal growth and development, complete penetrance	J:179977
	sinoatrial node hypoplasia	J:179977
	ventricular septal defect	J:179977
Tbx3tm1Jcib/Tbx3tm1Jcib involves: 129S4/SvJae * C57BL/6	abnormal fetal atrioventricular canal morphology	J:129349
	abnormal heart looping	J:129349
	abnormal vitelline vasculature morphology	J:129349
	decreased body size	J:129349
	delayed heart looping	J:129349
	failure of heart looping	J:129349
	pericardial edema	J:129349
	short hindlimb	J:129349
Tbx3tm1Pa/Tbx3+ either: (involves: 129 * 129S1/Sv * 129X1/SvJ) or (involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6NTac)	abnormal clitoris morphology	J:82458
	abnormal female reproductive system morphology	J:82458
	abnormal vagina orifice morphology	J:82458
Tbx3tm1Pa/Tbx3tm1Pa either: (involves: 129 * 129S1/Sv * 129X1/SvJ) or (involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6NTac)	abnormal digit morphology	J:82458
	abnormal embryonic autopod plate morphology	J:82458
	abnormal forelimb morphology	J:82458
	abnormal hindlimb morphology	J:82458
	abnormal hindlimb zeugopod morphology	J:82458
	abnormal limb development	J:82458
	abnormal limb morphology	J:82458
	abnormal mammary gland bud morphology	J:82458
	abnormal mammary gland embryonic development	J:82458
	abnormal pelvic girdle bone morphology	J:82458
	abnormal ulna morphology	J:82458
	abnormal visceral yolk sac endoderm morphology	J:82458
	abnormal vitelline vasculature morphology	J:82458
	absent carpal bone	J:82458
	absent mammary gland	J:82458
	absent metacarpal bones	J:82458
	absent vitelline blood vessels	J:82458
	embryonic lethality during organogenesis, incomplete penetrance	J:82458
	pale yolk sac	J:82458
	small hindlimb buds	J:82458
	small liver	J:82458
	thin apical ectodermal ridge	J:82458
Tbx3tm2.1Moon/Tbx3tm2.1Moon involves: 129 * BALB/cJ * C57BL/6 * FVB/N * SJL	abnormal impulse conducting system conduction	J:179977
	abnormal P wave	J:179977
	abnormal QRS complex	J:179977
	abnormal sinus arrhythmia	J:179977
	absent P wave	J:179977
	absent PR interval	J:179977
	atrioventricular block	J:179977
	decreased heart rate	J:179977
	increased heart rate variability	J:179977
	irregular heartbeat	J:179977
	premature death	J:179977
	preweaning lethality, incomplete penetrance	J:179977
	prolonged QRS complex duration	J:179977
	shortened PR interval	J:179977
	sinus bradycardia	J:179977
Tbx3tm2.1Moon/Tbx3tm2.1Moon involves: 129 * BALB/cJ * C57BL/6 * SJL	abnormal cardiovascular development	J:179977
	abnormal digit morphology	J:179977
	abnormal inferior vena cava morphology	J:179977
	absent carpal bone	J:179977
	absent fibula	J:179977
	absent tarsus bones	J:179977
	absent ulna	J:179977
	atrioventricular block	J:179977
	decreased heart rate	J:179977
	edema	J:179977
	normal embryo phenotype	J:179977
	increased cardiac muscle contractility	J:179977
	irregular heartbeat	J:179977
	oligodactyly	J:179977
	postnatal lethality, incomplete penetrance	J:179977
	prenatal lethality, incomplete penetrance	J:179977
	prolonged QRS complex duration	J:179977
	sinoatrial node hypoplasia	J:179977
	ventricular septal defect	J:179977
Tbx3tm2Moon/Tbx3+ involves: 129 * C57BL/6	irregular heartbeat	J:179977
Tbx3tm3.1Moon/Tbx3tm3.1Moon Tg(CAG-cre/Esr1*)5Amc/0 involves: 129 * C57BL/6	abnormal sinus arrhythmia	J:179977
	atrioventricular block	J:179977
Tbx3tm3.1Moon/Tbx3tm3.1Moon Tg(GATA6-cre)#Jbeb/0 involves: 129 * C57BL/6	atrioventricular block	J:179977
Tbx3tm3.1Moon/Tbx3tm3.1Moon Tg(Mef2c-cre)2Blk/0 involves: 129 * C57BL/6	atrioventricular block	J:179977
	embryonic lethality during organogenesis, incomplete penetrance	J:179977
	irregular heartbeat	J:179977
Tbx3tm3.2Moon/Tbx3tm3.2Moon involves: 129 * BALB/cJ * C57BL/6 * SJL	atrioventricular block	J:179977
	decreased heart rate	J:179977
	embryonic lethality, complete penetrance	J:179977
	irregular heartbeat	J:179977