Sp1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sp1
trans-acting transcription factor 1
MGI:98372

25 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Sp1^tm1Phi/Sp1⁺ Sp3^tm1Sus/Sp3⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal bone ossification	J:123073
	abnormal cranium morphology	J:123073
	abnormal erythropoiesis	J:123073
	abnormal liver sinusoid morphology	J:123073
	abnormal lung morphology	J:123073
	abnormal phalanx morphology	J:123073
	abnormal placenta intervillous maternal lacunae morphology	J:123073
	abnormal placenta morphology	J:123073
	anemia	J:123073
	anophthalmia	J:123073
	decreased body size	J:123073
	decreased erythroid progenitor cell number	J:123073
	decreased fetal weight	J:123073
	decreased liver weight	J:123073
	decreased placenta weight	J:123073
	decreased spongiotrophoblast cell number	J:123073
	decreased spongiotrophoblast size	J:123073
	decreased trophoblast glycogen cell number	J:123073
	disorganized placental labyrinth	J:123073
	hypovolemia	J:123073
	lethality at weaning, complete penetrance	J:123073
	lethality throughout fetal growth and development, incomplete penetrance	J:123073
	pallor	J:123073
	skin edema	J:123073
	small liver	J:123073

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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