Scn3a Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Scn3a
sodium channel, voltage-gated, type III, alpha
MGI:98249

6 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Scn3a^{Gt(OST52130)Lex}/\Scn3a⁺ involves: 129S5/SvEvBrd * C57BL/6J	improved glucose tolerance	J:103485
\Scn3a^{Gt(OST52130)Lex}/\Scn3a^{Gt(OST52130)Lex} involves: 129S5/SvEvBrd * C57BL/6J	decreased body size	J:103485
	lethargy	J:103485
	preweaning lethality, complete penetrance	J:103485
\Scn3a^tm1.1Jwo/\Scn3a^tm1.1Jwo involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:82809
\Scn3a^tm1.1Jwo/\Scn3a^tm1.1Jwo \Scn10a^tm2(cre)Jwo/\Scn10a⁺ involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	normal behavior/neurological phenotype	J:199857
\Scn3a^tm1.1Jwo/\Scn3a^tm1.1Jwo \Tg(Nefh-cre)22Jcol/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6	normal behavior/neurological phenotype	J:199857
\Scn3a^tm1.2Jwo/\Scn3a^tm1.2Jwo involves: 129S4/SvJaeSor * 129S6/SvEvTac * BALB/c * C57BL/6	no abnormal phenotype detected	J:199857

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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