Pth Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pth
parathyroid hormone
MGI:97799

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pth^tm1Dgo/Pth^tm1Dgo Pthlh^tm1Hmk/Pthlh^tm1Hmk involves: 129S2/SvPas * C57BL/6J	abnormal angiogenesis	J:76407
	abnormal appendicular skeleton morphology	J:76407
	abnormal axial skeleton morphology	J:76407
	abnormal bone mineralization	J:76407
	abnormal bone structure	J:76407
	abnormal cartilage development	J:76407
	abnormal long bone epiphyseal plate proliferative zone	J:76407
	abnormal long bone hypertrophic chondrocyte zone	J:76407
	abnormal osteoclast morphology	J:76407
	abnormal skeleton morphology	J:76407
	abnormal trabecular bone morphology	J:76407
	decreased length of long bones	J:76407
	decreased osteoblast cell number	J:76407
	decreased osteoclast cell number	J:76407
	disproportionate dwarf	J:76407
	enlarged parathyroid gland	J:76407
	increased chondrocyte apoptosis	J:76407
	increased compact bone thickness	J:76407
	increased osteoblast apoptosis	J:76407
	increased osteocyte apoptosis	J:76407
	increased width of hypertrophic chondrocyte zone	J:76407
	perinatal lethality, complete penetrance	J:76407
	short limbs	J:76407

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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