Prps1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prps1
phosphoribosyl pyrophosphate synthetase 1
MGI:97775

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prps1^tm1.1Xzl/Y involves: 129 * C57BL/6J	abnormal enzyme/coenzyme activity	J:388624
	cochlear ganglion degeneration	J:388624
	cochlear inner hair cell degeneration	J:388624
	cochlear outer hair cell degeneration	J:388624
	impaired hearing	J:388624
	increased or absent threshold for auditory brainstem response	J:388624
Prps1^tm1.1Xzl/Prps1^tm1.1Xzl involves: 129 * C57BL/6J	abnormal enzyme/coenzyme activity	J:388624
	cochlear ganglion degeneration	J:388624
	cochlear inner hair cell degeneration	J:388624
	cochlear outer hair cell degeneration	J:388624
	impaired hearing	J:388624
	increased or absent threshold for auditory brainstem response	J:388624
Prps1^{tm1b(EUCOMM)Wtsi}/Prps1⁺ C57BL/6N-Prps1^{tm1b(EUCOMM)Wtsi}/Ics	decreased lymphocyte cell number	J:211773
	increased circulating total protein level	J:211773
	increased neutrophil cell number	J:211773
Prps1^{tm1b(EUCOMM)Wtsi}/Prps1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Prps1^{tm1b(EUCOMM)Wtsi}/Ics	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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