Prkar2b Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkar2b
protein kinase, cAMP dependent regulatory, type II beta
MGI:97760

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
A^y/A Prkar2b^tm2Gsm/Prkar2b⁺ involves: C57BL/6	increased percent body fat/body weight	J:131039
	increased susceptibility to weight gain	J:131039
	polyphagia	J:131039
A^y/A Prkar2b^tm2Gsm/Prkar2b^tm2Gsm involves: C57BL/6	normal behavior/neurological phenotype	J:131039
	normal growth/size/body region phenotype	J:131039
	increased brown adipose tissue amount	J:131039
	increased gonadal fat pad weight	J:131039
	increased inguinal fat pad weight	J:131039
	increased locomotor activity	J:131039
	increased percent body fat/body weight	J:131039
	increased retroperitoneal fat pad weight	J:131039
	increased susceptibility to weight gain	J:131039
	yellow coat color	J:131039
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Drd1^tm1(cre)Rpa/Drd1⁺ involves: C57BL/6	normal adipose tissue phenotype	J:196157
	normal growth/size/body region phenotype	J:196157
	normal homeostasis/metabolism phenotype	J:196157
	hyperactivity	J:196157
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Slc32a1^tm2(cre)Lowl/Slc32a1⁺ involves: 129S6/SvEvTac * C57BL/6	normal adipose tissue phenotype	J:196157
	normal behavior/neurological phenotype	J:196157
	normal growth/size/body region phenotype	J:196157
	normal homeostasis/metabolism phenotype	J:196157
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Tg(Drd2-cre)ER44Gsat/0 involves: C57BL/6 * FVB/N	normal behavior/neurological phenotype	J:196157
	decreased body weight	J:196157
	decreased circulating leptin level	J:196157
	decreased total body fat amount	J:196157
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Tg(Ins2-cre)25Mgn/0 involves: C57BL/6 * DBA	normal adipose tissue phenotype	J:196157
	normal behavior/neurological phenotype	J:196157
	normal growth/size/body region phenotype	J:196157
	normal homeostasis/metabolism phenotype	J:196157
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	normal adipose tissue phenotype	J:196157
	normal behavior/neurological phenotype	J:196157
	normal growth/size/body region phenotype	J:196157
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Tg(Ppp1r1b-cre)1Meeh/0 involves: C57BL/6	normal behavior/neurological phenotype	J:196157
	decreased circulating leptin level	J:196157
	decreased lean body mass	J:196157
Prkar2b^tm3Gsm/Prkar2b^tm2Gsm Tg(Syn1-cre)671Jxm/0 involves: C57BL/6 * CBA	normal adipose tissue phenotype	J:196157
	normal behavior/neurological phenotype	J:196157
	normal growth/size/body region phenotype	J:196157

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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