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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ppia
peptidylprolyl isomerase A
MGI:97749
38 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ppiaem1(IMPC)Mbp/Ppiaem1(IMPC)Mbp
C57BL/6NCrl-Ppiaem1(IMPC)Mbp/MbpMmucd
abnormal auditory brainstem response J:211773
abnormal colon morphology J:211773
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal spleen morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased body length J:211773
decreased erythrocyte cell number J:211773
decreased heart weight J:211773
enlarged spleen J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
increased mean platelet volume J:211773
increased red blood cell distribution width J:211773
increased spleen weight J:211773
megacolon J:211773
microphthalmia J:211773
small kidney J:211773
Ppiatm1Lubn/Ppiatm1Lubn
129S6.129P2-Ppiatm1Lubn
abnormal CD4-positive, alpha-beta T cell physiology J:93591
blepharitis J:93591
heart inflammation J:93591
increased circulating interleukin-4 level J:93591
increased IgE level J:93591
increased IgG1 level J:93591
increased immunoglobulin level J:93591
increased inflammatory response J:93591
increased interleukin-2 secretion J:93591
increased interleukin-4 secretion J:93591
increased susceptibility to type I hypersensitivity reaction J:93591
increased T cell number J:93591
liver inflammation J:93591
pancreas inflammation J:93591
postnatal lethality, incomplete penetrance J:93591
prenatal lethality, incomplete penetrance J:93591
spleen hyperplasia J:93591
Ppiatm1Lubn/Ppiatm1Lubn
involves: 129P2/OlaHsd * MF1
prenatal lethality, incomplete penetrance J:93591

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory