Prkce Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkce
protein kinase C, epsilon
MGI:97599

16 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkce^m1Btlr/Prkce^m1Btlr C57BL/6J-Prkce^m1Btlr	decreased dendritic cell number	J:267703
Prkce^m1Btlr/Prkce^m1Btlr C57BL/6J-Prkce^m1Btlr	decreased NK cell number	J:267703
Prkce^tm1Bai/Prkce^tm1Bai Not Specified	normal immune system phenotype	J:94663
Prkce^tm1Bsca/Prkce^tm1Bsca involves: 129P2/OlaHsd * C57BL/6	abnormal uterus morphology	J:103337
	decreased body size	J:103337
	decreased circulating interleukin-1 beta level	J:103337
	decreased circulating tumor necrosis factor level	J:103337
	decreased macrophage apoptosis	J:103337
	decreased macrophage nitric oxide production	J:103337
	decreased T cell proliferation	J:103337
	decreased total body fat amount	J:103337
	dilated uterus	J:103337
	increased myocardial infarct size	J:102533
	increased susceptibility to bacterial infection	J:103337
	reduced female fertility	J:103337
Prkce^tm1Ltg/Prkce^tm1Ltg involves: 129P2/OlaHsd * FVB/N	decreased tumor necrosis factor secretion	J:86056

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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