Pou1f1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pou1f1
POU domain, class 1, transcription factor 1
MGI:97588

42 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pou1f1^dw-J/Pou1f1^dw-J C3H/HeJ-Pou1f1^dw-J/J	abnormal cerebellar foliation	J:110624
	abnormal cerebellar granule layer morphology	J:110624
	abnormal cerebellum development	J:110624
	abnormal dentate gyrus morphology	J:110624
	abnormal hippocampus pyramidal cell layer	J:110624
	abnormal hippocampus pyramidal cell morphology	J:110624
	decreased hippocampus pyramidal cell number	J:110624
	ectopic cerebellar granule cells	J:110624
Pou1f1^dw/Pou1f1^dw-J (DW/J x C3H/HeJ)F1	extended life span	J:73731
Pou1f1^dw/Pou1f1^dw DW/J Pou1f1^dw	abnormal adenohypophysis morphology	J:108961
	absent lactotrophs	J:7211
	absent somatotrophs	J:7211
	adenohypophysis hypoplasia	J:108961
	decreased B cell number	J:110683
	decreased body size	J:108961
	extended life span	J:73731
	increased pituitary gland apoptosis	J:108961
Pou1f1^dw/Pou1f1^dw Not Specified	abnormal actin cytoskeleton morphology	J:144823
	abnormal cochlear outer hair cell morphology	J:144823
	abnormal hair cell physiology	J:144823
	abnormal Hensen stripe morphology	J:144823
	abnormal molar root morphology	J:13120
	abnormal orientation of outer hair cell stereociliary bundles	J:144823
	abnormal pillar cell morphology	J:144823
	abnormal stria vascularis morphology	J:144823
	abnormal strial intermediate cell morphology	J:144823
	abnormal tectorial membrane morphology	J:144823
	abnormal tectorial membrane striated-sheet matrix morphology	J:144823
	abnormal tunnel of Corti morphology	J:144823
	absent cochlear microphonics	J:144823
	absent distortion product otoacoustic emissions	J:144823
	absent lactotrophs	J:6754
	absent somatotrophs	J:7211
	cochlear outer hair cell degeneration	J:144823
	deafness	J:144823
	decreased circulating prolactin level	J:6754
	decreased endocochlear potential	J:144823
	decreased growth hormone level	J:6589
	decreased prolactin level	J:6589
	decreased thyrotroph cell number	J:12161
	infertility	J:13120
	proportional dwarf	J:13120
	short cochlear outer hair cells	J:144823
Pou1f1^em1(IMPC)Bay/Pou1f1^em1(IMPC)Bay C57BL/6N-Pou1f1^em1(IMPC)Bay/BayMmucd	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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