Pde6a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pde6a
phosphodiesterase 6A, cGMP-specific, rod, alpha
MGI:97524

17 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pde6a^em1(IMPC)Mbp/Pde6a^em1(IMPC)Mbp C57BL/6NCrl-Pde6a^em1(IMPC)Mbp/Mmucd	abnormal eye morphology	J:211773
	abnormal heart morphology	J:211773
	enlarged heart	J:211773
	increased circulating phosphate level	J:211773
Pde6a^em2(IMPC)Mbp/Pde6a^em2(IMPC)Mbp C57BL/6N-Pde6a^em2(IMPC)Mbp/Ucd	abnormal coat/ hair morphology	J:211773
Pde6a^nmf282/Pde6a^nmf282 A.B6 Tyr⁺-Pde6a^nmf282/J	abnormal electroretinogram waveform feature	J:142108
	abnormal ocular fundus morphology	J:142108
	absent photoreceptor outer segment	J:142108
	brain vacuoles	J:87349
	decreased retina photoreceptor cell number	J:142108
	retina degeneration	J:87349
	retina photoreceptor degeneration	J:142108
	retina spots	J:87349
	short photoreceptor inner segment	J:142108
	short photoreceptor outer segment	J:142108
	thin retina outer nuclear layer	J:142108
Pde6a^nmf282/Pde6a^nmf282 involves: A/J * C57BL/6J	decreased retina photoreceptor cell number	J:142108
	retina photoreceptor degeneration	J:142108
	short photoreceptor outer segment	J:142108
	thin retina outer nuclear layer	J:142108
Pde6a^nmf282/Pde6a^nmf363 involves: A/J * C57BL/6J	retina photoreceptor degeneration	J:142108
	short photoreceptor outer segment	J:142108
	thin retina outer nuclear layer	J:142108
Pde6a^nmf282/Pde6a^tvrm58 involves: A/J * C57BL/6J	retina degeneration	J:214072
Pde6a^nmf363/Pde6a^nmf363 C57BL/6J-Pde6a^nmf363/J	abnormal eye electrophysiology	J:142108
	retina photoreceptor degeneration	J:142108
	thin retina outer nuclear layer	J:142108
Pde6a^nmf363/Pde6a^nmf363 involves: A/J * C57BL/6J	decreased retina photoreceptor cell number	J:142108
	retina photoreceptor degeneration	J:142108
	short photoreceptor outer segment	J:142108
	thin retina outer nuclear layer	J:142108
Pde6a^tvrm58/Pde6a^tvrm58 involves: C57BL/6J	abnormal ocular fundus morphology	J:214072
	retina degeneration	J:166679, J:214072
	thin retina outer nuclear layer	J:214072

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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