45 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pcsk2em1(IMPC)H/Pcsk2+ C57BL/6NTac-Pcsk2em1(IMPC)H/H	increased circulating alanine transaminase level	J:211773
Pcsk2em1(IMPC)H/Pcsk2em1(IMPC)H C57BL/6NTac-Pcsk2em1(IMPC)H/H	abnormal coat/ hair morphology	J:211773
	abnormal locomotor behavior	J:211773
	decreased circulating glucose level	J:211773
	increased circulating amylase level	J:211773
	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating iron level	J:211773
	increased mean corpuscular volume	J:211773
	limb grasping	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Pcsk2tm1Dfs/Pcsk2tm1Dfs B6;129-Pcsk2tm1Dfs/J	abnormal pancreatic alpha cell differentiation	J:236905
	abnormal pancreatic alpha cell morphology	J:236905
	decreased circulating glucagon level	J:236905
	decreased glucagon secretion	J:236905
	dilated renal tubule	J:236905
	enlarged pancreatic islets	J:236905
	improved glucose tolerance	J:236905
	increased circulating insulin level	J:236905
	increased glucagonoma incidence	J:236511
	increased pancreas tumor incidence	J:236905
	increased pancreatic alpha cell number	J:236905
	increased pancreatic ductal adenocarcinoma incidence	J:236905
	increased pancreatic islet cell adenoma incidence	J:236905
	pancreatic islet hyperplasia	J:236905
	premature death	J:236905
Pcsk2tm1Dfs/Pcsk2tm1Dfs involves: 129S1/Sv * 129X1/SvJ	normal homeostasis/metabolism phenotype	J:184882
	normal mortality/aging	J:184882
Pcsk2tm1Dfs/Pcsk2tm1Dfs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal gland physiology	J:41505
	abnormal pancreatic beta cell differentiation	J:85590
	abnormal pancreatic islet morphology	J:41505
	abnormal pancreatic somatostatin secretion	J:41505
	decreased circulating glucose level	J:41505
	decreased circulating insulin level	J:41505
	decreased glucagon secretion	J:41505
	decreased insulin secretion	J:41505
	decreased pancreatic beta cell number	J:41505
	decreased pituitary hormone level	J:82967
	impaired glucose tolerance	J:41505
	increased pancreatic alpha cell mass	J:41505
	increased pancreatic alpha cell proliferation	J:85590
	increased pancreatic delta cell number	J:41505
	increased systemic arterial blood pressure	J:82967
	reduced female fertility	J:41505
Pcsk2tm1Dfs/Pcsk2tm1Dfs involves: 129S1/Sv * 129X1/SvJ * CD-1	analgesia	J:112641
	hyporesponsive to tactile stimuli	J:112641
	increased thermal nociceptive threshold	J:112641