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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nppc
natriuretic peptide type C
MGI:97369
31 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nppclbab/Nppclbab
B6.PL-Nppclbab/GrsrJ 		abnormal endochondral bone ossification J:321139
abnormal female meiosis J:164870
abnormal long bone epiphyseal plate proliferative zone J:321139
decreased body length J:122924, J:321139
decreased body size J:321139
decreased body weight J:122924, J:321139
decreased bone volume J:321139
decreased long bone epiphyseal plate size J:321139
decreased trabecular bone thickness J:321139
decreased width of hypertrophic chondrocyte zone J:321139
disproportionate dwarf J:122924
postnatal lethality, complete penetrance J:122924
short limbs J:122924
Nppclbab/Nppclbab
either: (involves: C57BL/6J * PL/J) or PL/J 		abnormal long bone epiphyseal plate morphology J:79175
decreased body size J:79175
decreased length of long bones J:79175
disorganized long bone epiphyseal plate J:79175
disproportionate dwarf J:79175
normal reproductive system phenotype J:79175
short fibula J:79175
short tail J:79175
short tibia J:79175
small testis J:79175
Nppclbab/Nppclbab
involves: PL/J 		abnormal sensory neuron innervation pattern J:153212
Nppctm1.1Fgr/Nppctm1.1Fgr
involves: 129P2/OlaHsd * C57BL/6J 		abnormal miniature excitatory postsynaptic currents J:153212
abnormal neuron physiology J:153212
abnormal sensory neuron innervation pattern J:153212
decreased body height J:153212
decreased physiological sensitivity to xenobiotic J:153212
Nppctm1.1Fgr/Nppctm1.1Fgr
Tg(Thy1-YFP)HJrs/0
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA 		abnormal sensory neuron innervation pattern J:153212
Nppctm1Yog/Nppctm1Yog
either: 129X1/SvJ or (involves: 129 * C57BL/6J) 		abnormal cartilage morphology J:75620
abnormal long bone epiphyseal plate proliferative zone J:75620
abnormal vertebral epiphyseal plate morphology J:75620
decreased body length J:75620
decreased body weight J:75620
decreased cranium height J:75620
decreased long bone epiphyseal plate size J:75620
decreased width of hypertrophic chondrocyte zone J:75620
disproportionate dwarf J:75620
postnatal growth retardation J:75620
postnatal lethality, incomplete penetrance J:75620
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory