Mgmt Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mgmt
O-6-methylguanine-DNA methyltransferase
MGI:96977

8 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mgmt^{tm1b(EUCOMM)Wtsi}/Mgmt^{tm1b(EUCOMM)Wtsi} C57BL/6N-Mgmt^{tm1b(EUCOMM)Wtsi}/Tcp	decreased prepulse inhibition	J:211773
	increased blood urea nitrogen level	J:211773
Mgmt^tm1Lds/Mgmt^tm1Lds involves: 129P2/OlaHsd * C57BL/6	increased circulating glucose level	J:118148
	increased susceptibility to injury	J:118148
	small pancreatic islets	J:118148
Mgmt^tm1Mse/Mgmt^tm1Mse involves: 129S/SvEv	increased physiological sensitivity to xenobiotic	J:47642
	increased susceptibility to induced morbidity/mortality	J:47642
	increased T cell derived lymphoma incidence	J:47642

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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