Mc2r Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mc2r
melanocortin 2 receptor
MGI:96928

24 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mc2r^tm1Dchi/Mc2r^tm1Dchi B6.129P2-Mc2r^tm1Dchi	abnormal adrenal gland capsule morphology	J:127445
	abnormal adrenal gland zona fasciculata morphology	J:127445
	abnormal gluconeogenesis	J:127445
	abnormal glucose homeostasis	J:127445
	adrenal gland hypoplasia	J:127445
	decreased circulating adrenaline level	J:127445
	decreased circulating aldosterone level	J:127445
	decreased circulating corticosterone level	J:127445
	decreased heart rate	J:127445
	decreased total body fat amount	J:127445
	hypoglycemia	J:127445
	increased circulating adrenocorticotropin level	J:127445
	increased circulating chloride level	J:127445
	increased circulating potassium level	J:127445
	increased spleen weight	J:127445
	increased thymus weight	J:127445
	lethargy	J:127445
	postnatal lethality, incomplete penetrance	J:127445
Mc2r^tm1Dgen/Mc2r^tm1Dgen involves: 129P2/OlaHsd * C57BL/6J	adrenal cortical hyperplasia	J:82809
	adrenal gland hypoplasia	J:82809
	decreased brown fat lipid droplet number	J:82809
	decreased percent body fat/body weight	J:82809
	increased anxiety-related response	J:82809
	increased locomotor activity	J:82809
	increased susceptibility to pharmacologically induced seizures	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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