Mbl1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mbl1
mannose-binding lectin (protein A) 1
MGI:96923

10 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mbl1^tm1.1Mnz/Mbl1^tm1.1Mnz B6.129-Mbl1^tm1.1Mnz	normal immune system phenotype	J:84540
Mbl1^tm1Kata/Mbl1^tm1Kata involves: 129S4/SvJae * C57BL/6J	decreased circulating tumor necrosis factor level	J:90437
Mbl1^tm1Kata/Mbl1^tm1Kata involves: 129S4/SvJae * C57BL/6J	decreased susceptibility to induced morbidity/mortality	J:90437
Mbl1^tm1Rala/Mbl1^tm1Rala involves: 129X1/SvJ * C57BL/6J	abnormal immunoglobulin level	J:145279
	decreased IgG2b level	J:145279
	decreased IgM level	J:145279
	increased IgG1 level	J:145279
	increased IgG2a level	J:145279
	increased IgG3 level	J:145279
	increased susceptibility to parasitic infection	J:145279

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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