Maoa Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Maoa
monoamine oxidase A
MGI:96915

28 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Maoa^K284stop/Y 129S6/SvEvTac-Maoa^K284stop	decreased locomotor activity	J:136818
Maoa^K284stop/Y 129S6/SvEvTac-Maoa^K284stop	increased aggression towards male mice	J:136818
Maoa^{Tg(H2-K1-Ifnb1)8Seif}/Y involves: C3H/HeJ	abnormal behavior	J:26232
	abnormal cerebral cortex morphology	J:26232
	abnormal depression-related behavior	J:26232
	abnormal eating behavior	J:26232
	abnormal grooming behavior	J:26232
	abnormal motor coordination/balance	J:26232
	abnormal sexual interaction	J:26232
	abnormal sleep pattern	J:26232
	abnormal social investigation	J:26232
	abnormal social/conspecific interaction behavior	J:26232
	head bobbing	J:26232
	hunched posture	J:26232
	hyperresponsive	J:26232
	impaired balance	J:26232
	impaired righting response	J:26232
	increased aggression towards humans	J:26232
	increased aggression towards male mice	J:26232
	increased dopamine level	J:26232
	increased fear-related response	J:26232
	increased noradrenaline level	J:26232
	increased serotonin level	J:26232
Maoa^{Tg(H2-K1-Ifnb1)8Seif}/? involves: C3H/HeJ	abnormal behavior	J:26232
	abnormal cerebral cortex morphology	J:26232
	abnormal circulating hormone level	J:106365
	abnormal depression-related behavior	J:26232
	abnormal eating behavior	J:26232
	abnormal grooming behavior	J:26232
	abnormal motor coordination/balance	J:26232
	abnormal motor neuron morphology	J:78281
	abnormal nervous system electrophysiology	J:78281
	abnormal sleep pattern	J:26232
	abnormal social/conspecific interaction behavior	J:26232
	head bobbing	J:26232
	hunched posture	J:26232
	hyperresponsive	J:26232
	impaired balance	J:26232
	impaired righting response	J:26232
	increased aggression towards humans	J:26232
	increased dopamine level	J:26232
	increased fear-related response	J:26232
	increased noradrenaline level	J:26232
	increased serotonin level	J:26232, J:78281
Maoa^tm1Shih/Maoa^tm1Shih involves: 129S4/SvJae	abnormal myocardial fiber physiology	J:170067
	decreased left ventricle systolic pressure	J:170067
	decreased response of heart to induced stress	J:170067

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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