Krt8 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Krt8
keratin 8
MGI:96705

17 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Krt8^tm1Rgo/Krt8^tm1Rgo Tnf^tm1Gkl/Tnf^tm1Gkl involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * FVB/N	normal mortality/aging	J:121811
	prenatal lethality, incomplete penetrance	J:121811
Krt8^tm1Rgo/Krt8^tm1Rgo Tnfrsf1b^tm1Mwm/Tnfrsf1b^tm1Mwm involves: 129S2/SvPas * C57BL/6 * FVB/N	embryonic lethality during organogenesis, incomplete penetrance	J:121811
Krt19^tm2Mmt/Krt19^tm2Mmt Krt8^tm1Rgo/Krt8^tm1Rgo FVB.129S2-Krt19^tm2Mmt Krt8^tm1Rgo	abnormal allantois morphology	J:65498
	abnormal placenta labyrinth morphology	J:65498
	abnormal placenta morphology	J:65498
	abnormal placental labyrinth vasculature morphology	J:65498
	abnormal spongiotrophoblast cell morphology	J:65498
	abnormal spongiotrophoblast layer morphology	J:65498
	abnormal trophoblast giant cell morphology	J:65498
	abnormal trophoblast layer morphology	J:65498
	decreased spongiotrophoblast cell number	J:65498
	embryonic growth retardation	J:65498
	embryonic lethality during organogenesis, complete penetrance	J:65498
	impaired placental function	J:65498
	increased trophoblast giant cell number	J:65498
	small placenta	J:65498

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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