Krt1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Krt1
keratin 1
MGI:96698

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Krt1^Mhdadsk12/Krt1⁺ C3HeB/FeJ-Krt1^Mhdadsk12	abnormal skin pigmentation	J:108758
	acanthosis	J:108758
	blistering	J:108758
	hyperkeratosis	J:108758
	hyperpigmentation	J:108758
	scaly skin	J:108758
Krt1^Mhdadsk12/Krt1^Mhdadsk12 C3HeB/FeJ-Krt1^Mhdadsk12	blistering	J:108758
	dehydration	J:108758
	epidermal desquamation	J:108758
	postnatal lethality, complete penetrance	J:108758
Krt1^tm1Tmm/Krt1^tm1Tmm involves: 129 * C57BL/6	abnormal blood cell morphology/development	J:200244
	abnormal cerebellar granule layer morphology	J:200244
	abnormal circulating interleukin level	J:200244
	abnormal corneocyte envelope morphology	J:200244
	abnormal interleukin secretion	J:200244
	abnormal skin morphology	J:200244
	abnormal vasculogenesis	J:200244
	impaired skin barrier function	J:200244
	increased circulating interleukin-18 level	J:200244
	increased vascular permeability	J:200244
	neonatal lethality, incomplete penetrance	J:200244
	weight loss	J:200244

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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