Jund Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Jund
jun D proto-oncogene
MGI:96648

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Jun^{tm6.1(Jund)Wag}/Jun^{tm6.1(Jund)Wag} Jund^tm1Mya/Jund^tm1Mya involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6	decreased fibroblast proliferation	J:175212
	early cellular replicative senescence	J:175212
	embryonic growth retardation	J:175212
	embryonic lethality during organogenesis, complete penetrance	J:175212
Jund^tm1Mya/Jund^tm1Mya Tg(H2-K-Fosl1)1Wag/0 involves: 129S2/SvPas * C57BL/6 * CBA	abnormal mitochondrial physiology	J:95691
	abnormal myocardial fiber mitochondrial morphology	J:95691
	ascites	J:95691
	cardiac hypertrophy	J:95691
	cardiac interstitial fibrosis	J:95691
	congestive heart failure	J:95691
	dilated cardiomyopathy	J:95691
	edema	J:95691
	lethargy	J:95691
	liver vascular congestion	J:95691
	postnatal lethality, incomplete penetrance	J:95691
	pulmonary vascular congestion	J:95691
	respiratory distress	J:95691
	visceral vascular congestion	J:95691

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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