Itgb7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Itgb7
integrin beta 7
MGI:96616

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Itgb7^tm1Cgn/Itgb7^tm1Cgn C57BL/6-Itgb7^tm1Cgn/J	abnormal leukocyte migration	J:127413
Itgb7^tm1Cgn/Itgb7^tm1Cgn C57BL/6-Itgb7^tm1Cgn/J	colitis	J:127413
Itgb7^tm1Cgn/Itgb7^tm1Cgn involves: C57BL/6	abnormal gut-associated lymphoid tissue morphology	J:34306
	abnormal immune system morphology	J:34306
	abnormal immune system physiology	J:34306
	abnormal lymphocyte physiology	J:34306
	abnormal myometrium morphology	J:44813
	abnormal Peyer's patch follicle morphology	J:34306
	abnormal response to infection	J:62733
	abnormal uterine NK cell morphology	J:44813
	decreased B cell number	J:34306
	decreased CD4-positive, alpha-beta T cell number	J:34306
	decreased eosinophil cell number	J:62733
	decreased mast cell number	J:62733
	normal immune system phenotype	J:111227
	impaired leukocyte tethering or rolling	J:34306
	increased susceptibility to parasitic infection	J:90262
	increased trophoblast giant cell number	J:44813
	increased uterine NK cell number	J:44813
	small Peyer's patches	J:34306
Itgb7^tm1Mshi/Itgb7^tm1Mshi involves: C57BL/6	abnormal leukocyte adhesion	J:127413
	abnormal leukocyte migration	J:127413
	colitis	J:127413
	small Peyer's patches	J:127413

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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