Irf2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Irf2
interferon regulatory factor 2
MGI:96591

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Irf2^tm1Mak/Irf2⁺ either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * C57BL/6J * DBA/2)	no abnormal phenotype detected	J:64286
Irf2^tm1Mak/Irf2^tm1Mak either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * C57BL/6J * DBA/2)	abnormal immune system physiology	J:64286
	abnormal response to infection	J:64286
	decreased B cell proliferation	J:64286
	decreased IgG2a level	J:64286
	decreased mature B cell number	J:64286
	decreased T cell number	J:64286
	normal immune system phenotype	J:64286
	premature death	J:64286
	skin lesions	J:64286
Irf2^tm1Mak/Irf2^tm1Mak involves: 129S2/SvPas * C57BL/6	dermatitis	J:66034
	enlarged inguinal lymph nodes	J:66034
	increased memory T cell number	J:66034
	lymph node hyperplasia	J:66034
	premature hair loss	J:66034
	reddish skin	J:66034
	skin fibrosis	J:66034
	skin lesions	J:66034
	thick epidermis	J:66034

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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