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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Irf2
interferon regulatory factor 2
MGI:96591
18 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Irf2tm1Mak/Irf2+
either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * C57BL/6J * DBA/2)
no abnormal phenotype detected J:64286
Irf2tm1Mak/Irf2tm1Mak
either: (involves: 129S2/SvPas * C57BL/6J) or (involves: 129S2/SvPas * C57BL/6J * DBA/2)
abnormal immune system physiology J:64286
abnormal response to infection J:64286
decreased B cell proliferation J:64286
decreased IgG2a level J:64286
decreased mature B cell number J:64286
decreased T cell number J:64286
normal immune system phenotype J:64286
premature death J:64286
skin lesions J:64286
Irf2tm1Mak/Irf2tm1Mak
involves: 129S2/SvPas * C57BL/6
dermatitis J:66034
enlarged inguinal lymph nodes J:66034
increased memory T cell number J:66034
lymph node hyperplasia J:66034
premature hair loss J:66034
reddish skin J:66034
skin fibrosis J:66034
skin lesions J:66034
thick epidermis J:66034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory