Hoxb8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hoxb8
homeobox B8
MGI:96189

30 phenotypes from 8 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Hoxb8^tm1.1Jdes/\Hoxb8⁺ involves: 129P2/OlaHsd * FVB	abnormal dorsal root ganglion morphology	J:58621
	abnormal spinal nerve morphology	J:58621
	abnormal sternocostal joint morphology	J:58621
\Hoxb8^tm1.1Jdes/\Hoxb8^tm1.1Jdes involves: 129P2/OlaHsd * FVB	abnormal dorsal root ganglion morphology	J:58621
	abnormal gait	J:58621
	abnormal rib morphology	J:68720
	abnormal sternocostal joint morphology	J:58621
	abnormal sternum morphology	J:68720
	asymmetric rib joints	J:68720
	cervical vertebral transformation	J:68720
	limb grasping	J:58621
	postnatal growth retardation	J:58621
	skin lesions	J:58621
\Hoxb8^tm1.1Mrc/\Hoxb8^tm1.1Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal coat appearance	J:73745
	abnormal skin condition	J:73745
	abnormal sleep pattern	J:73745
	increased grooming behavior	J:73745
	normal nervous system phenotype	J:73745
	normal skeleton phenotype	J:73745
\Hoxb8^tm1.1Mrc/\Hoxb8^tm1.1Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal grooming behavior	J:162102
	abnormal microglial cell morphology	J:162102
	abnormal spinal cord dorsal horn morphology	J:162102
	focal hair loss	J:162102
	increased grooming behavior	J:162102
	increased thermal nociceptive threshold	J:162102
	skin lesions	J:162102
\Hoxb8^tm1Jdes/\Hoxb8^tm1Jdes involves: 129P2/OlaHsd * FVB	abnormal dorsal root ganglion morphology	J:58621
	abnormal gait	J:58621
	abnormal rib morphology	J:58621
	abnormal vertebral column morphology	J:58621
	limb grasping	J:58621
	postnatal growth retardation	J:58621
	skin lesions	J:58621
\Hoxb8^tm1Mrc/\Hoxb8^tm1Mrc involves: 129S1/Sv * 129X1/SvJ	abnormal coat appearance	J:73745
	abnormal rib development	J:73745
	abnormal skin condition	J:73745
	increased grooming behavior	J:73745
\Hoxb8^tm1Omm/\Hoxb8⁺ involves: 129S7/SvEvBrd	thoracic vertebral transformation	J:86684
\Hoxb8^tm1Omm/\Hoxb8⁺ involves: 129S7/SvEvBrd * C57BL/6	thoracic vertebral transformation	J:86684
\Hoxb8^tm1Omm/\Hoxb8^tm1Omm involves: 129S7/SvEvBrd	abnormal rib morphology	J:86684
	abnormal sternocostal joint morphology	J:86684
	decreased sternebra number	J:86684
	rib fusion	J:86684
	thoracic vertebral transformation	J:86684
\Hoxb8^tm1Omm/\Hoxb8^tm1Omm involves: 129S7/SvEvBrd * C57BL/6	abnormal rib morphology	J:86684
	abnormal sternocostal joint morphology	J:86684
	abnormal tooth morphology	J:86684
	decreased sternebra number	J:86684
	premature death	J:86684
	rib fusion	J:86684
	thoracic vertebral transformation	J:86684
\Hoxb8^tm2Jdes/\Hoxb8^tm2Jdes involves: 129P2/OlaHsd * FVB	limb grasping	J:58621
\Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc}/\Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc} \Hoxc8^{tm2.1(cre)Mrc}/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal spinal cord dorsal horn morphology	J:162102
	normal behavior/neurological phenotype	J:162102
	increased thermal nociceptive threshold	J:162102
\Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc}/\Hoxb8^{tm3.1(IRES-rtTA2M2)Mrc} \Tg(Tek-cre)1Arnd/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * DBA/2	normal behavior/neurological phenotype	J:162102
	focal hair loss	J:162102
	increased grooming behavior	J:162102
	normal nervous system phenotype	J:162102
\Hoxb8^{tm4.1(cre/Esr1)Mrc}/\Hoxb8^{tm4.1(cre/Esr1)Mrc} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	skin lesions	J:162102

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24