70 phenotypes from 4 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hoxa5tm1.1Ljea/Hoxa5+ Tg(Sftpc-cre)1Blh/0 involves: 129 * C57BL/6J * DBA/2 * SJL	abnormal pulmonary alveolar sac morphology	J:170336
	lung cyst	J:170336
Hoxa5tm1.1Ljea/Hoxa5tm1.1Ljea involves: 129/Sv * 129S4/SvJaeSor * C57BL/6J * SJL	no abnormal phenotype detected	J:125040
Hoxa5tm1.1Ljea/Hoxa5tm1.1Ljea Tg(Hoxa5-cre)444CLjea/0 involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal cervical vertebrae morphology	J:207917
	abnormal xiphoid process morphology	J:207917
	normal mortality/aging	J:207917
	normal respiratory system phenotype	J:207917
Hoxa5tm1.1Ljea/Hoxa5tm1.1Ljea Tg(Hoxa5-cre)447BLjea/0 involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal cervical vertebrae morphology	J:207917
	abnormal lung development	J:207917
	abnormal pulmonary alveolus morphology	J:207917
	abnormal trachea morphology	J:207917
	abnormal xiphoid process morphology	J:207917
	increased rib number	J:207917
	perinatal lethality, incomplete penetrance	J:207917
	respiratory distress	J:207917
Hoxa5tm1.1Ljea/Hoxa5tm1.1Ljea Tg(Sftpc-cre)1Blh/0 involves: 129 * C57BL/6J * DBA/2 * SJL	abnormal pulmonary alveolar sac morphology	J:170336
	lung cyst	J:170336
Hoxa5tm1.2Ljea/Hoxa5tm1.2Ljea involves: 129/Sv * C57BL/6 * CBA * SJL	abnormal cervical vertebrae morphology	J:125040
	abnormal pulmonary alveolus morphology	J:125040
	abnormal tracheal cartilage morphology	J:125040
	atelectasis	J:125040
	cricoid and tracheal cartilage fusion	J:125040
	emphysema	J:125040
	increased respiratory mucosa goblet cell number	J:125040
	neonatal lethality, incomplete penetrance	J:125040
Hoxa5tm1Ljea/Hoxa5tm1Ljea involves: 129/Sv * C57BL/6J * SJL	abnormal cervical vertebrae morphology	J:125040
	abnormal tracheal cartilage morphology	J:125040
	atelectasis	J:125040
	cricoid and tracheal cartilage fusion	J:125040
	neonatal lethality, incomplete penetrance	J:125040
Hoxa5tm1Rob/Hoxa5tm1Rob 129S(Cg)-Hoxa5tm1Rob	abnormal branching involved in lung morphogenesis	J:45341
	abnormal bronchiole epithelium morphology	J:45341
	abnormal bronchiole morphology	J:45341
	abnormal bronchus epithelium morphology	J:45341
	abnormal cricoid cartilage morphology	J:45341
	abnormal digestive secretion	J:58676
	abnormal estrous cycle	J:182519
	abnormal larynx morphology	J:45341
	abnormal lung saccule morphology	J:45341
	abnormal pulmonary acinus morphology	J:45341
	abnormal thyroid gland development	J:84449
	abnormal trachea morphology	J:45341
	abnormal tracheal cartilage morphology	J:45341
	atelectasis	J:45341
	cricoid and tracheal cartilage fusion	J:45341
	cyanosis	J:45341
	decreased surfactant secretion	J:84449
	decreased tracheal cartilage ring number	J:45341
	delayed ear emergence	J:84449
	delayed eyelid opening	J:45341, J:84449
	early sexual maturation	J:182519
	impaired branching involved in respiratory bronchiole morphogenesis	J:45341
	increased circulating estradiol level	J:182519
	increased circulating thyroid-stimulating hormone level	J:84449
	meteorism	J:45341
	neonatal lethality, incomplete penetrance	J:45341
	ovary cyst	J:182519
	postnatal growth retardation	J:45341, J:84449
	postnatal lethality, incomplete penetrance	J:45341
	prolonged diestrus	J:182519
	prolonged estrous cycle	J:182519
	prolonged metestrus	J:182519
	respiratory distress	J:45341
	short estrus	J:182519
	trachea occlusion	J:45341
	trachea stenosis	J:45341
Hoxa5tm1Rob/Hoxa5tm1Rob B6.129S(Cg)-Hoxa5tm1Rob	abnormal cricoid cartilage morphology	J:45341
	abnormal trachea morphology	J:45341
	atelectasis	J:45341
	decreased surfactant secretion	J:45341
	decreased tracheal cartilage ring number	J:45341
	delayed eyelid opening	J:45341
	impaired branching involved in bronchus morphogenesis	J:45341
	meteorism	J:45341
	neonatal lethality, incomplete penetrance	J:45341
	postnatal growth retardation	J:45341
	postnatal lethality, incomplete penetrance	J:45341
	thick pulmonary interalveolar septum	J:45341
	trachea occlusion	J:45341
Hoxa5tm1Rob/Hoxa5tm1Rob involves: 129S/SvEv * C57BL/6 * MF1	abnormal alveolar macrophage morphology	J:113378
	abnormal lung weight	J:113378
	abnormal pulmonary alveolar parenchyma morphology	J:113378
	abnormal pulmonary alveolus morphology	J:113378
	abnormal pulmonary elastic fiber morphology	J:113378
	abnormal pulmonary interalveolar septum morphology	J:113378
	abnormal respiratory mucosa goblet cell morphology	J:113378
	abnormal surfactant secretion	J:113378
	atelectasis	J:113378
	emphysema	J:113378
	impaired lung alveolus development	J:113378
	increased respiratory mucosa goblet cell number	J:113378
	increased type II pneumocyte number	J:113378
	lung inflammation	J:113378
	overexpanded pulmonary alveolus	J:113378
Hoxa5tm1Rob/Hoxa5tm1Rob involves: 129S/SvEv * MF1	abnormal rib morphology	J:15576
	abnormal vertebrae morphology	J:15576
	asymmetric sternocostal joints	J:15576
	cervical vertebral transformation	J:15576
	increased rib number	J:15576
	increased sternebra number	J:15576
	lumbar vertebral transformation	J:15576
	postnatal lethality, incomplete penetrance	J:15576
	rib fusion	J:15576
	sternebra fusion	J:15576