About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nrg1
neuregulin 1
MGI:96083
11 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Bace1tm1Psa/Bace1tm1Psa
Nrg1tm4.1Cbm/Nrg1+
involves: 129P2/OlaHsd * 129S2/SvPas * BALB/cJ * C57BL/6 		abnormal muscle spindle morphology J:199150
decreased muscle spindle number J:199150
Bace1tm1Psa/Bace1tm1Psa
Tg(Thy1-Nrg1*I)1Kan/0
involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 		decreased muscle spindle number J:199150
normal nervous system phenotype J:199150
Erbb2tm1Cbm/Erbb2+
Nrg1tm1Cbm/Nrg1+
involves: 129P2/OlaHsd 		abnormal myelination J:90038
abnormal nerve conduction J:90038
Erbb2tm1Cbm/Erbb2+
Erbb3tm2Cbm/Erbb3+
Nrg1tm1Cbm/Nrg1+
involves: 129P2/OlaHsd 		abnormal myelination J:90038
abnormal nerve conduction J:90038
Nrg1tm1Cbm/Nrg1tm3Cbm
Isl2tm1Arbr/Isl2+
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J 		abnormal motor neuron innervation pattern J:69623
abnormal motor neuron morphology J:69623
abnormal nervous system development J:69623
abnormal neuromuscular synapse morphology J:69623
absent Schwann cells J:69623
neonatal lethality, incomplete penetrance J:69623
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory