H2-I Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-I
H2 I region, includes H2-Aa, Ab, Bl, Ea, Eb, Eb2, Ob, Pb
MGI:95903

7 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(H2-Ea)16Dim/? involves: C57BL/6 * SJL	increased immunoglobulin level	J:111128
Tg(H2-Ea^d)5Lt/0 NOD/ShiLt-Tg(H2-Ea^d)5Lt	autoimmune response	J:36435
	decreased interferon-gamma secretion	J:36435
	decreased susceptibility to autoimmune diabetes	J:36435
	increased interleukin-4 secretion	J:36435
	periinsulitis	J:36435
Tg(H2-Ea^d)12Lt/0 NOD/ShiLt-Tg(H2-Ea^d)12Lt	autoimmune response	J:36435
	decreased interferon-gamma secretion	J:36435
	decreased susceptibility to autoimmune diabetes	J:36435
	increased interleukin-4 secretion	J:36435
	insulitis	J:36435

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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