H2-Aa Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

H2-Aa
histocompatibility 2, class II antigen A, alpha
MGI:95895

8 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
H2-Aa^b-tm1Blt/H2-Aa^b-tm1Blt C57BL/6-H2-Aa^b-tm1Blt	abnormal MHC II cell surface expression on macrophages	J:67924
	abnormal splenocyte physiology	J:16372
	abnormal T cell morphology	J:16372
	decreased CD4-positive, alpha-beta T cell number	J:16372
	enlarged lymph nodes	J:16372
	enlarged thymus	J:16372
	increased CD8-positive, alpha-beta T cell number	J:16372
	thymus hyperplasia	J:16372

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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