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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ets1
E26 avian leukemia oncogene 1, 5' domain
MGI:95455
55 phenotypes from 7 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ets1m1Anu/Ets1m1Anu
C57BL/6NCrlAnu-Ets1m1Anu
normal immune system phenotype J:104190
Ets1tm1.1Dds/Ets1+
129S6/SvEvTac-Ets1tm1.1Dds
abnormal thymus morphology J:121460
decreased memory T cell number J:121460
decreased thymocyte apoptosis J:121460
enlarged thymus J:121460
increased splenocyte apoptosis J:121460
increased thymus weight J:121460
Ets1tm1.1Dds/Ets1tm1.1Dds
129S6/SvEvTac-Ets1tm1.1Dds
abnormal CD8-positive, alpha beta T cell morphology J:121460
abnormal lymphopoiesis J:121460
abnormal spleen morphology J:121460
abnormal spleen red pulp morphology J:121460
abnormal thymus cortex morphology J:121460
abnormal thymus morphology J:121460
abnormal thymus subcapsular epithelium morphology J:121460
decreased B cell number J:121460
decreased CD4-positive, alpha-beta T cell number J:121460
decreased leukocyte cell number J:121460
decreased memory T cell number J:121460
decreased spleen weight J:121460
decreased thymocyte apoptosis J:121460
enlarged thymus J:121460
increased cell proliferation J:121460
increased double-positive T cell number J:121460
increased splenocyte apoptosis J:121460
increased thymus weight J:121460
perinatal lethality, incomplete penetrance J:121460
prenatal lethality, incomplete penetrance J:121460
small spleen J:121460
Ets1tm1Fwa/Ets1tm1Fwa
B6.129S4-Ets1tm1Fwa
abnormal B cell differentiation J:93845
absent B-1a cells J:93845
decreased B cell number J:93845
decreased B cell proliferation J:93845
decreased body weight J:93454, J:93845
decreased mature B cell number J:93845
decreased pro-B cell number J:93845
normal immune system phenotype J:93845
increased B cell apoptosis J:93845
increased pro-B cell number J:93845
postnatal growth retardation J:93454, J:93845
postnatal lethality, incomplete penetrance J:93454, J:93845
Ets1tm1Jml/Ets1tm1Jml
involves: 129S/SvEv * C57BL/6
abnormal CD8-positive, alpha-beta T cell differentiation J:125056
decreased CD4-positive, alpha-beta T cell number J:125056
decreased CD8-positive, alpha-beta T cell number J:125056
increased double-negative T cell number J:125056
thymus hypoplasia J:125056
Ets1tm1Most/Ets1tm1Most
Pax3tm1(cre)Joe/Pax3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
double outlet right ventricle J:334073
Ets1tm2Jml/Ets1+
involves: 129X1/SvJ * C57BL/6J
belly spot J:334073
Ets1tm2Jml/Ets1tm2Jml
involves: 129X1/SvJ * C57BL/6
abnormal CD8-positive, alpha beta T cell morphology J:50627
abnormal leukocyte physiology J:50627
abnormal NK cell physiology J:50627
abnormal T cell activation J:50627
decreased NK cell number J:50627
decreased T cell number J:50627
decreased T cell proliferation J:50627
decreased thymocyte number J:50627
normal hematopoietic system phenotype J:50627
impaired natural killer cell mediated cytotoxicity J:50627
increased plasma cell number J:50627
perinatal lethality, incomplete penetrance J:50627
postnatal lethality, incomplete penetrance J:50627
Ets1tm2Jml/Ets1tm2Jml
involves: 129X1/SvJ * C57BL/6J
abnormal cardiac outflow tract development J:334073
abnormal heart right ventricle outflow tract morphology J:334073
bicuspid aortic valve J:334073
decreased cardiac neural crest cell number J:334073
double outlet right ventricle J:334073
overriding aortic valve J:334073
Ets1vs/Ets1vs
C3HeB/FeJ-Ets1vs/J
belly spot J:14217
head blaze J:14217
white spotting J:14217

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory