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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Drd2
dopamine receptor D2
MGI:94924
40 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Adora2atm1Jfc/Adora2atm1Jfc
Drd2tm1Low/Drd2tm1Low
involves: 129 * C57BL/6 		abnormal locomotor activation J:102700
Cm/+
Drd2tm1Low/Drd2tm1Low
involves: 101/H * 129S2/SvPas * C3H/HeH * C3H/HeSn * C57BL/6J 		normal behavior/neurological phenotype J:156905
decreased dopamine level J:156905
decreased locomotor activity J:156905
normal nervous system phenotype J:156905
Drd1tm1Jcd/Drd1+
Drd2tm1Ebo/Drd2tm1Ebo
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		normal mortality/aging J:91781
Drd1tm1Jcd/Drd1tm1Jcd
Drd2tm1Ebo/Drd2+
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal duodenum morphology J:91781
abnormal eating behavior J:91781
abnormal stomach morphology J:91781
gastrointestinal hemorrhage J:91781
intestinal ulcer J:91781
postnatal growth retardation J:91781
premature death J:91781
small intestinal inflammation J:91781
Drd1tm1Jcd/Drd1tm1Jcd
Drd2tm1Ebo/Drd2tm1Ebo
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal digestive system development J:91781
abnormal digestive system physiology J:91781
abnormal hypothalamus physiology J:91781
abnormal intestinal smooth muscle morphology J:91781
abnormal intestine morphology J:91781
absent gastric milk in neonates J:91781
aphagia J:91781
decreased body size J:91781
decreased locomotor activity J:91781
gastrointestinal hemorrhage J:91781
normal nervous system phenotype J:91781
postnatal growth retardation J:91781
postnatal lethality, complete penetrance J:91781
Drd2tm1(IL2RA)Koba/Drd2+
B6.129P2-Drd2tm1(IL2RA)Koba 		abnormal locomotor activation J:85929
decreased dopaminergic neuron number J:85929
unidirectional circling J:85929
Drd2tm1Ebo/Drd2tm1Ebo
Drd3tm1Dac/Drd3tm1Dac
involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 		abnormal behavior J:96229
abnormal defecation J:96229
abnormal emotion/affect behavior J:96229
decreased locomotor activity J:96229
decreased vertical activity J:96229
Drd2tm1Low/Drd2tm1Low
Tg(GFAP-CRYAB)141.6Mes/0
involves: 129S2/SvPas * C57BL/6 * FVB/N 		normal nervous system phenotype J:194407
Drd2tm1Schm/Drd2+
Drd3tm1Schm/Drd3tm1Schm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal locomotor behavior J:79483
Drd2tm1Schm/Drd2tm1Schm
Drd3tm1Schm/Drd3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal dopamine level J:79483
abnormal locomotor behavior J:79483
Drd2tm1Schm/Drd2tm1Schm
Drd3tm1Schm/Drd3tm1Schm
B6.Cg-Drd2tm1Schm Drd3tm1Schm 		abnormal intestinal absorption J:106280
abnormal intestinal transit time J:106280
abnormal large intestinal transit time J:106280
decreased body weight J:106280
increased defecation amount J:106280
increased fluid intake J:106280
increased food intake J:106280
Drd2tm1Schm/Drd2tm1Schm
Drd3tm1Schm/Drd3tm1Schm
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal dopamine level J:79483
abnormal locomotor behavior J:79483
decreased body weight J:79483
hunched posture J:79483
postnatal lethality, incomplete penetrance J:79483
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory