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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp1r1b
protein phosphatase 1, regulatory inhibitor subunit 1B
MGI:94860
15 phenotypes from 6 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ppp1r1btm1Aaf/Ppp1r1btm1Aaf
B6.129-Ppp1r1btm1Aaf 		abnormal alcohol consumption J:66956
hyperactivity elicited by ethanol administration J:66956
impaired conditioned place preference behavior J:66956
Ppp1r1btm1Aaf/Ppp1r1btm1Aaf
B6.129P2-Ppp1r1btm1Aaf 		impaired behavioral response to addictive substance J:107305
Ppp1r1btm1Aaf/Ppp1r1btm1Aaf
involves: 129P2/OlaHsd * C57BL/6J 		decreased physiological sensitivity to xenobiotic J:78045
impaired behavioral response to addictive substance J:78045
impaired behavioral response to cocaine J:78045
Ppp1r1btm1Aaf/Ppp1r1btm1Aaf
Not Specified 		decreased physiological sensitivity to xenobiotic J:54156
enhanced behavioral response to cocaine J:54156
Ppp1r1btm1Pggd/Ppp1r1btm1Pggd
involves: 129 * C57BL/6 		abnormal physiological response to xenobiotic J:106270
impaired behavioral response to addictive substance J:107305
impaired behavioral response to cocaine J:106270
Ppp1r1btm2Pggd/Ppp1r1btm2Pggd
involves: 129 * C57BL/6 		normal behavior/neurological phenotype J:106270
impaired behavioral response to addictive substance J:107305
Ppp1r1btm3Pggd/Ppp1r1btm3Pggd
involves: 129 * C57BL/6 		abnormal physiological response to xenobiotic J:106270
impaired behavioral response to addictive substance J:107305
impaired behavioral response to cocaine J:106270
Ppp1r1btm4Pggd/Ppp1r1btm4Pggd
involves: 129 * C57BL/6 		normal behavior/neurological phenotype J:106270
Ppp1r1btm4Pggd/Ppp1r1btm4Pggd
Not Specified 		abnormal behavior J:137074
impaired behavioral response to cocaine J:137074
impaired behavioral response to morphine J:137074
impaired conditioned place preference behavior J:137074
Ppp1r1btm5.1Pggd/Ppp1r1btm5.1Pggd
Tg(Drd1-cre)EY262Gsat/0
Tg(Drd1-EGFP)X60Gsat/0
involves: C57BL/6 * FVB/N * FVB/NTac 		decreased locomotor activity J:163700
impaired behavioral response to cocaine J:163700
impaired behavioral response to xenobiotic J:163700
reduced long-term potentiation J:163700
Ppp1r1btm5.1Pggd/Ppp1r1btm5.1Pggd
Tg(Drd2-cre)ER44Gsat/0
Tg(Drd2-EGFP)S118Gsat/0
involves: C57BL/6 * FVB/N * FVB/NTac 		enhanced behavioral response to cocaine J:163700
hyperactivity J:163700
impaired behavioral response to xenobiotic J:163700
reduced long-term potentiation J:163700
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory