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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
MGI:892986
15 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Spibtm1Ksho/Spibtm1Ksho
involves: C57BL/6J
abnormal intestine morphology J:187649
abnormal Peyer's patch morphology J:187649
normal digestive/alimentary phenotype J:187649
increased susceptibility to bacterial infection J:187649
Spibtm1Mcs/Spibtm1Mcs
involves: 129S1/Sv * 129X1/SvJ
abnormal humoral immune response J:45245
abnormal spleen B cell follicle morphology J:45245
abnormal spleen germinal center morphology J:45245
abnormal spleen white pulp morphology J:45245
decreased B cell proliferation J:45245
decreased IgG1 level J:45245
decreased IgG2a level J:45245
decreased IgG2b level J:45245
increased B cell apoptosis J:45245
increased IgM level J:45245
Spibtm1Mcs/Spibtm1Mcs
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
abnormal immature B cell morphology J:88257
decreased B cell proliferation J:88257

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory