Cyp2e1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
MGI:88607

12 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cyp2e1^{tm1b(KOMP)Wtsi}/Cyp2e1^{tm1b(KOMP)Wtsi} C57BL/6N-Cyp2e1^{tm1b(KOMP)Wtsi}/H	abnormal tooth morphology	J:211773
Cyp2e1^tm1Gonz/Cyp2e1^tm1Gonz involves: 129S4/SvJae	abnormal blood homeostasis	J:143909
	abnormal hepatocyte morphology	J:118150
	abnormal physiological response to xenobiotic	J:143909
	abnormal xenobiotic pharmacokinetics	J:143909
	decreased incidence of tumors by chemical induction	J:118150
	dilated vasculature	J:118150
	enhanced behavioral response to xenobiotic	J:143909
	hepatic steatosis	J:112076
	increased susceptibility to xenobiotic induced morbidity/mortality	J:143909
Cyp2e1^tm1Gonz/Cyp2e1^tm1Gonz involves: 129S4/SvJae * C57BL/6N	decreased physiological sensitivity to xenobiotic	J:48196
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:48196

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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