Ctsb Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ctsb
cathepsin B
MGI:88561

11 phenotypes from 1 allele in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ctsb^tm1Jde/Ctsb⁺ NOD.129P2-Ctsb^tm1Jde	decreased susceptibility to autoimmune diabetes	J:153355
	hyperglycemia	J:153355
	insulitis	J:153355
Ctsb^tm1Jde/Ctsb^tm1Jde either: (involves: 129P2/OlaHsd * 129/Sv) or (involves: 129P2/OlaHsd * C57BL/6)	normal immune system phenotype	J:47432
	normal renal/urinary system phenotype	J:172774
Ctsb^tm1Jde/Ctsb^tm1Jde involves: 129P2/OlaHsd	decreased apoptosis	J:96164
Ctsb^tm1Jde/Ctsb^tm1Jde involves: 129P2/OlaHsd * C57BL/6J	abnormal thyroid gland morphology	J:83877
	abnormal thyroid hormone level	J:83877
	amyloidosis	J:116135
	decreased susceptibility to induced pancreatitis	J:64872
Ctsb^tm1Jde/Ctsb^tm1Jde NOD.129P2-Ctsb^tm1Jde	decreased susceptibility to autoimmune diabetes	J:153355
	hyperglycemia	J:153355
	insulitis	J:153355
	salivary gland inflammation	J:153355

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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