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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Crybb2
crystallin, beta B2
MGI:88519
28 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Crybb20377/Crybb2+
involves: C3H * C57BL/6Ei
abnormal lens morphology J:136138
cataract J:136138
small lens J:136138
Crybb20377/Crybb20377
involves: C3H * C57BL/6Ei
abnormal lens morphology J:136138
cataract J:136138
decreased Purkinje cell size J:136138
increased Purkinje cell number J:136138
small lens J:136138
Crybb2Aey2/Crybb2+
C3HeB/FeJ-Crybb2Aey2
abnormal lens fiber morphology J:70508
abnormal lens morphology J:70508
cataract J:70508
total cataract J:70508
Crybb2Lop19/Crybb2+
SJL/J-Crybb2Lop19/BocJ
cataract J:187061
sutural cataract J:187061
total cataract J:187061
Crybb2Phil/Crybb2Phil
Swiss Webster
abnormal lens morphology J:6293
nuclear cataract J:6293
subcapsular cataract J:6293
Crybb2tm1Itl/Crybb2tm1Itl
C57BL/6-Crybb2tm1Itl
abnormal cell cycle J:220082
anterior cortical cataract J:142278
cataract J:142278
decreased circulating progesterone level J:220082
decreased granulosa cell proliferation J:220082
decreased litter size J:220082
decreased mature ovarian follicle number J:220082
decreased mitotic index J:220082
decreased primordial ovarian follicle number J:220082
decreased secondary ovarian follicle number J:220082
decreased superovulation rate J:220082
impaired ovarian folliculogenesis J:220082
increased atretic ovarian follicle number J:220082
increased cellular sensitivity to hydrogen peroxide J:142278
increased circulating estradiol level J:220082
increased granulosa cell apoptosis J:220082
microphthalmia J:142278
posterior cortical cataract J:142278
reduced female fertility J:220082
small lens J:142278
total cataract J:142278

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory