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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
C4b
complement C4B (Chido blood group)
MGI:88228
27 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
C4bem1(IMPC)H/C4bem1(IMPC)H
C57BL/6NTac-C4bem1(IMPC)H/H
decreased lean body mass J:211773
increased freezing behavior J:211773
C4btm1Crr/C4btm1Crr
involves: 129S4/SvJae
abnormal blood coagulation J:44715
decreased susceptibility to Coronaviridae infection J:286325
glomerulonephritis J:44715
C4btm1Crr/C4btm1Crr
involves: 129S4/SvJae * C57BL/6
abnormal humoral immune response J:64282
abnormal intestine morphology J:78613
abnormal spleen germinal center morphology J:64282
decreased spleen germinal center number J:64282
decreased spleen germinal center size J:64282
decreased susceptibility to bacterial infection J:30152
decreased vascular permeability J:78613
normal homeostasis/metabolism phenotype J:120567
normal immune system phenotype J:30152, J:64282
increased susceptibility to bacterial infection induced morbidity/mortality J:30152
increased susceptibility to induced morbidity/mortality J:44240
liver inflammation J:30152
C4btm1Crr/C4btm1Crr
involves: 129S4/SvJae * C57BL/6J
abnormal immune system physiology J:111811
abnormal renal glomerulus morphology J:111811
glomerulonephritis J:111811
increased anti-double stranded DNA antibody level J:111811
increased anti-nuclear antigen antibody level J:111811
increased anti-single stranded DNA antibody level J:111811
increased macrophage cell number J:111811
increased neutrophil cell number J:111811
increased spleen germinal center number J:111811
increased spleen weight J:111811
renal glomerular protein deposits J:111811

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory