Apex1 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apex1
apurinic/apyrimidinic endonuclease 1
MGI:88042

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Apex1^tm1Djc/\Apex1⁺ \Tg(TacLIZa)A1Jsh/0 involves: 129X1/SvJ * C57BL/6 * NTac:NIHBS	abnormal cell physiology	J:92957
	abnormal DNA repair	J:92957
\Apex1^tm1Ecf/\Apex1⁺ \Xpc^tm1Ecf/\Xpc^tm1Ecf involves: 129	increased tumor incidence	J:70397
\Apex1^tm1Ecf/\Apex1⁺ \Xpc^tm1Ecf/\Xpc^tm1Ecf involves: 129	oxidative stress	J:70397

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24