Acta2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acta2
actin alpha 2, smooth muscle, aorta
MGI:87909

10 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Acta2^em1(IMPC)H/Acta2^em1(IMPC)H C57BL/6NTac-Acta2^em1(IMPC)H/H	decreased heart weight	J:211773
Acta2^tm1Rjs/Acta2^tm1Rjs involves: 129S7/SvEvBrd * C57	abnormal aorta elastic tissue morphology	J:113261
	abnormal aorta morphology	J:113261
	abnormal blood flow velocity	J:113261
	abnormal systemic arterial blood pressure	J:113261
	decreased systemic arterial systolic blood pressure	J:113261
	decreased vasoconstriction	J:113261
Acta2^tm1Rjs/Acta2^tm1Rjs involves: 129S7/SvEvBrd * C57BL/6	abnormal cone electrophysiology	J:111893
	abnormal rod electrophysiology	J:111893
	increased vascular permeability	J:111893

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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